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Datasheets/Manuals | Printable datasheet for Goat Anti-SHP2 / PTPN11 Antibody (OAEB01811) |
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Predicted Species Reactivity | Bovine|Human|Mouse|Porcine|Rat |
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Product Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Clonality | Polyclonal |
Host | Goat |
Application | WB, IHC |
Reconstitution and Storage | Aliquot and store at -20C. Minimize freezing and thawing. |
Immunogen | PTPN11 |
Purification | Ammonium Sulfate Precipitated; Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Cow: 100%; Guinea Pig: 100%; Horse: 100%; Rabbit: 100%; Zebrafish: 92% |
Peptide Sequence | C-YENVGLMQQQKSFR |
Concentration | 0.5 mg/ml |
Purity | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Application Info | Peptide ELISA: antibody detection limit dilution 1:32000. Western Blot: Approx 70kDa band observed in Human Skeletal Muscle lysates and in lysates of cell line HEK293 (calculated MW of 68.0kDa according to NP_002825.3). In transfected HEK293 transiently expressing PTPN11 bands of approx. 70kDa and 49kDa are observed. These bands are not observed in the non-transfected HEK293. Recommended for use at 1-3ug/ml. |
Reference | * Takagi K, Takagi M, Kanangat S, Warrington KJ, Shigemitsu H, Postlethwaite AE.; Modulation of TNF-alpha gene expression by IFN-gamma and pamidronate in murine macrophages: regulation by STAT1-dependent pathways.; J Immunol. 2005 Feb 15;174(4):1801-10.; Pubmed 15699106 * Saxton TM, Ciruna BG, Holmyard D, Kulkarni S, Harpal K, Rossant J, Pawson T.; The SH2 tyrosine phosphatase shp2 is required for mammalian limb development.; Nat Genet 2000 Apr;24(4):420-3; Pubmed 10742110 |
Gene Symbol | Ptpn11|PTPN11 |
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Gene Full Name | protein tyrosine phosphatase non-receptor type 11|protein tyrosine phosphatase, non-receptor type 11 |
Alias Symbols | 2700084A17Rik;AW536184;BPTP3;CFC;encodes catalytic domain;JMML;METCDS;NS1;protein tyrosine phosphatase SH-PTP2;protein-tyrosine phosphatase 1D;protein-tyrosine phosphatase 2C;protein-tyrosine phosphatase SYP;PTP;PTP1D;PTP-1D;PTP2C;S;SAP-2;Sh;SH2 domain-containing protein tyrosine phosphatase 2;SH2 domain-containing protein tyrosine phosphatase-2;SHP;SH-P;Shp2;SHP-2;SH-PTP2;SH-PTP2 protein tyrosine phosphatase, non-receptor type 11;SH-PTP3;Syp;tyrosine-protein phosphatase non-receptor type 11. |
NCBI Gene Id | 19247|25622|5781 |
Protein Name | Tyrosine-protein phosphatase non-receptor type 11 |
Uniprot ID | Q06124 |
Protein Accession # | NP_002825.3 |
Molecular Weight | 68.0; 68.4 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Goat Anti-SHP2 / PTPN11 Antibody (OAEB01811)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Bovine|Human|Mouse|Porcine|Rat".
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How long will it take to receive "Goat Anti-SHP2 / PTPN11 Antibody (OAEB01811)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "Goat Anti-SHP2 / PTPN11 Antibody (OAEB01811)" provided in?
This item is provided in "Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Goat Anti-SHP2 / PTPN11 Antibody (OAEB01811)"?
This target may also be called "2700084A17Rik;AW536184;BPTP3;CFC;encodes catalytic domain;JMML;METCDS;NS1;protein tyrosine phosphatase SH-PTP2;protein-tyrosine phosphatase 1D;protein-tyrosine phosphatase 2C;protein-tyrosine phosphatase SYP;PTP;PTP1D;PTP-1D;PTP2C;S;SAP-2;Sh;SH2 domain-containing protein tyrosine phosphatase 2;SH2 domain-containing protein tyrosine phosphatase-2;SHP;SH-P;Shp2;SHP-2;SH-PTP2;SH-PTP2 protein tyrosine phosphatase, non-receptor type 11;SH-PTP3;Syp;tyrosine-protein phosphatase non-receptor type 11." in publications.
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What is the shipping cost for "Goat Anti-SHP2 / PTPN11 Antibody (OAEB01811)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Goat Anti-SHP2 / PTPN11 Antibody (OAEB01811)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Goat Anti-SHP2 / PTPN11 Antibody (OAEB01811)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "68.0; 68.4".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Goat Anti-SHP2 / PTPN11 Antibody (OAEB01811)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "Ptpn11|PTPN11"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "Ptpn11|PTPN11"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "Ptpn11|PTPN11"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "Ptpn11|PTPN11"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "Ptpn11|PTPN11"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "Ptpn11|PTPN11"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.