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Catalog No: OAEB02455 (Formerly GWB-49EE5F)
Size:100UG
Price: $379.00
SKU
OAEB02455
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for Goat Anti-ABCC4 / MRP4 Antibody (OAEB02455)
Product Info
Predicted Species ReactivityHuman|Mouse|Rat
Product FormatSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
ClonalityPolyclonal
HostGoat
ApplicationIHC-P, P-WB, IF
Reconstitution and StorageAliquot and store at -20C. Minimize freezing and thawing.
ImmunogenABCC4
PurificationAmmonium Sulfate Precipitated; Affinity Purified
Predicted Homology Based on Immunogen SequenceHuman, Mouse, Rat
Peptide SequenceCNGQPSTLTIFETAL
Concentration0.5 mg/ml
SpecificityThis antibody is expected to recognize isoform 1 (NP_005836.2) only.
Application InfoP-ELISA 1:32000
WB 1.0~3.0 ug/ml, 170 kDa band observed in rat renal cortex membranes.
IHC 2.0~4.0 ug/ml. Shows strong cytoplasmic staining in small flat basal cells and weak cytoplasmic staining in the columnar secretory cells of the epithelium.
IF Used successfully in human primary hepatocytes as describied in Xu et al, Am J Physiol Gastrointest Liver Physiol. 2010 Jul;200(1):G126-35, PMID: 20395535.
Reference* Schuetz JD, Connelly MC, Sun D, Paibir SG, Flynn PM, Srinivas RV, Kumar A, Fridland A.; MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs.; Nat Med. 1999 Sep;5(9):1048-51.; Pubmed 10470083
Publications

Gori, I. et al. Augmented epithelial multidrug resistance-associated protein 4 expression in peritoneal endometriosis: regulation by lipoxin A(4). Fertil. Steril. 99, 1965-73.e2 (2013). 23472950

Montani, M. et al. Multidrug resistance protein 4 (MRP4) expression in prostate cancer is associated with androgen signaling and decreases with tumor progression. Virchows Arch. 462, 437-43 (2013). 23503867

Weerachayaphorn, J. et al. Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine. Am. J. Physiol. Gastrointest. Liver Physiol. 302, G925-36 (2012). 22345550

Xu, S., Weerachayaphorn, J., Cai, S.-Y., Soroka, C. J. & Boyer, J. L. Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression. Am. J. Physiol. Gastrointest. Liver Physiol. 299, G126-35 (2010). 20395535

Gene SymbolAbcc4|ABCC4
Gene Full NameATP binding cassette subfamily C member 4
Alias SymbolsABC-tranporter;ATP-binding cassette protein C4;ATP-binding cassette subfamily C member 4;ATP-binding cassette sub-family C member 4;ATP-binding cassette, subfamily C (CFTR/MRP), member 4;ATP-binding cassette, sub-family C (CFTR/MRP), member 4;bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4);canalicular multispecific organic anion transporter (ABC superfamily);MOATB;MOAT-B;MRP/cMOAT-related ABC transporter;Mrp4;multidrug resistance-associated protein 4;multi-specific organic anion transporter B;RGD1565953.
NCBI Gene Id10257|170924
Protein NameMultidrug resistance-associated protein 4
Uniprot IDO15439
Protein Accession #NP_005836.2
Molecular Weight150
  1. What is the species homology for "Goat Anti-ABCC4 / MRP4 Antibody (OAEB02455)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".

  2. How long will it take to receive "Goat Anti-ABCC4 / MRP4 Antibody (OAEB02455)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "Goat Anti-ABCC4 / MRP4 Antibody (OAEB02455)" provided in?

    This item is provided in "Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Goat Anti-ABCC4 / MRP4 Antibody (OAEB02455)"?

    This target may also be called "ABC-tranporter;ATP-binding cassette protein C4;ATP-binding cassette subfamily C member 4;ATP-binding cassette sub-family C member 4;ATP-binding cassette, subfamily C (CFTR/MRP), member 4;ATP-binding cassette, sub-family C (CFTR/MRP), member 4;bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4);canalicular multispecific organic anion transporter (ABC superfamily);MOATB;MOAT-B;MRP/cMOAT-related ABC transporter;Mrp4;multidrug resistance-associated protein 4;multi-specific organic anion transporter B;RGD1565953." in publications.

  5. What is the shipping cost for "Goat Anti-ABCC4 / MRP4 Antibody (OAEB02455)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Goat Anti-ABCC4 / MRP4 Antibody (OAEB02455)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Goat Anti-ABCC4 / MRP4 Antibody (OAEB02455)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "150".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Goat Anti-ABCC4 / MRP4 Antibody (OAEB02455)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "Abcc4|ABCC4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "Abcc4|ABCC4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "Abcc4|ABCC4"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "Abcc4|ABCC4"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "Abcc4|ABCC4"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "Abcc4|ABCC4"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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