- Toll Free: 888-880-0001
- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for GCH1 Antibody (OAEB01449) |
|---|
| Predicted Species Reactivity | Human|Mouse|Rat |
|---|---|
| Product Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Clonality | Polyclonal |
| Host | Goat |
| Application | WB |
| Reconstitution and Storage | Aliquot and store at -20C. Minimize freezing and thawing. |
| Immunogen | GCH1 |
| Purification | Ammonium Sulfate Precipitated; Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 91%; Rabbit: 100%; Rat: 91%; Zebrafish: 90% |
| Peptide Sequence | C-GKVHIGYLPNKQ |
| Concentration | 0.5 mg/ml |
| Purity | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Application Info | Peptide ELISA: antibody detection limit dilution 1:16000. Western Blot: Approx. 37kDa band observed in Human Lymph Node, Thymus and Tonsil lysates. Customer's experiments gave identical results in lysates of cell line HUVEC with antibodies raised against different parts of the same protein. (calculated MW of 27.9kDa according to NP_000152.1). Recommended concentration: 1-3ug/ml. |
| Reference | * Tegeder I, Costigan M, Griffin RS, Abele A, Belfer I, Schmidt H, Ehnert C, Nejim J, Marian C, Scholz J, Wu T, Allchorne A, Diatchenko L, Binshtok AM, Goldman D, Adolph J, Sama S, Atlas SJ, Carlezon WA, Parsegian A, Lotsch J, Fillingim RB, Maixner W, Geisslinger G, Max MB, Woolf CJ.; GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence.; Nat Med. 2006 Nov;12(11):1269-77. Epub 2006 Oct 22.; Pubmed 17057711 |
| Gene Symbol | Gch1|GCH1 |
|---|---|
| Gene Full Name | GTP cyclohydrolase 1 |
| Alias Symbols | dystonia 14;DYT14;DYT5;DYT5a;GCH;GTP cyclohydrase I;GTP cyclohydrolase 1;GTP cyclohydrolase I;GTPC;GTP-C;GTPCH;GTP-CH;GTPCH1;GTP-CH-1;GTP-CH-I;guanosine 5'-triphosphate cyclohydrolase I;HPABH4B. |
| NCBI Gene Id | 14528|2643|29244 |
| Protein Name | GTP cyclohydrolase 1 |
| Uniprot ID | P30793 |
| Protein Accession # | NP_000152.1 |
| Molecular Weight | 27.9; 25.8; 23.5 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
-
What is the species homology for "GCH1 Antibody (OAEB01449)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".
-
How long will it take to receive "GCH1 Antibody (OAEB01449)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
-
What buffer format is "GCH1 Antibody (OAEB01449)" provided in?
This item is provided in "Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "GCH1 Antibody (OAEB01449)"?
This target may also be called "dystonia 14;DYT14;DYT5;DYT5a;GCH;GTP cyclohydrase I;GTP cyclohydrolase 1;GTP cyclohydrolase I;GTPC;GTP-C;GTPCH;GTP-CH;GTPCH1;GTP-CH-1;GTP-CH-I;guanosine 5'-triphosphate cyclohydrolase I;HPABH4B." in publications.
-
What is the shipping cost for "GCH1 Antibody (OAEB01449)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
-
What is the guarantee for "GCH1 Antibody (OAEB01449)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
-
Can I get bulk pricing for "GCH1 Antibody (OAEB01449)"?
You can get bulk pricing for this item by going here.
-
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "27.9; 25.8; 23.5".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "GCH1 Antibody (OAEB01449)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
-
What are positive controls for "Gch1|GCH1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What are negative controls for "Gch1|GCH1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What other proteins interact with "Gch1|GCH1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
-
What biological processes are associated with "Gch1|GCH1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
-
What cellular components are associated with "Gch1|GCH1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
-
What protein functions are associated with "Gch1|GCH1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
