website statistics

Aviva Systems Biology office will be closed for Memorial Day - 5/29/2017.
Please go here for more info.

Now Offering Over 102,157 Antibodies & 44,722 Antigens!

GCDH antibody - C-terminal region (ARP43559_T100)

Scroll Horizontally to view all Images
Print Page
  • Let us Help: Ask a Question
100 ul
$229.00
In Stock

Conjugation Options

ARP43559_T100-FITC Conjugated

ARP43559_T100-HRP Conjugated

ARP43559_T100-Biotin Conjugated

Gene Symbol:
GCDH
NCBI Gene Id:
2639
Official Gene Full Name:
Glutaryl-CoA dehydrogenase
Protein Name:
Glutaryl-CoA dehydrogenase, mitochondrial
Swissprot Id:
Q92947
Protein Accession #:
NP_000150
Nucleotide Accession #:
NM_000159
Alias Symbols:
ACAD5, GCD
Replacement Item:
This antibody may replace item sc-133610 from Santa Cruz Biotechnology.
Description of Target:
GCDH belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits.The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
Protein Size (# AA):
438
Molecular Weight:
48kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Protein A purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express GCDH.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express GCDH.
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human GCDH
Species Reactivity:
Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
Predicted Homology Based on Immunogen Sequence:
Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Complete computational species homology data:
Anti-GCDH (ARP43559_T100)
Peptide Sequence:
Synthetic peptide located within the following region: IARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITG
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; FBXO6; ADRB2; RNF32; EXOC6; ECSIT; MAST1; CDC37; PSEN2; PSEN1; NOS3; APOE; A2M; UBD; MYC; GCDH;
Blocking Peptide:
For anti-GCDH (ARP43559_T100) antibody is Catalog # AAP43559 (Previous Catalog # AAPP25004)
Datasheets / Downloads:
Printable datasheet for anti-GCDH (ARP43559_T100) antibody
Additional Information:
IHC Information: HepG2 cell lysate. Antibody concentration: 2.5 ug/ml. Gel concentration: 12%.
Target Reference:
Kimura,K., (2006) Genome Res. 16 (1), 55-65
Publications:

Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). WB, Human, Rat, Dog, Horse, Rabbit, Pig, Mouse, Zebrafish 24465277

 
X
Ask a Question

Tell us what you think about this item!

Write A Review
    Please, wait...