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100ug
$229.00
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GCDH antibody - C-terminal region (ARP43559_T100)

Description of Target:
GCDH belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits.The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene Symbol:
GCDH
Official Gene Full Name:
Glutaryl-CoA dehydrogenase
NCBI Gene Id:
2639
Alias Symbols:
ACAD5; GCD
Tissue Tool:
Find tissues and cell lines supported to express GCDH.
Protein Accession #:
NP_000150
Nucleotide Accession#:
NM_000159
Swissprot Id:
Q92947
Host:
Rabbit
Clonality:
Polyclonal
Protein Name:
Glutaryl-CoA dehydrogenase, mitochondrial
Protein Size (# AA):
438
Molecular Weight:
48kDa
Application:
IHC, WB
Partner Proteins:
CSTF2, EEF1G, PAFAH1B3, SERPINB9, TIMP1, TLR10, CSTF2, EEF1G, PAFAH1B3, SERPINB9, TIMP1
Immunogen:
The immunogen for anti-GCDH antibody: synthetic peptide directed towards the C terminal of human GCDH
Product Format:
Lyophilized powder
Purification:
Protein A purified
Complete computational species homology data:
GCDH antibody - C-terminal region (ARP43559_T100)
Predicted Homology Based on Immunogen Sequence:
Dog: 100%; Pig: 100%; Rat: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Zebrafish: 100%
Species Reactivity:
Human, Rat, Dog, Horse, Rabbit, Pig, Mouse, Zebrafish
Datasheets / Downloads:
Printable datasheet for
anti-GCDH antibody
- ARP43559_T100
Peptide Sequence:
Synthetic peptide located within the following region: IARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITG
Blocking Peptide:
For anti-GCDH antibody is Catalog # AAP43559 (Previous Catalog # AAPP25004)
Additional Information:
IHC Information: HepG2 cell lysate. Antibody concentration: 2.5 ug/ml. Gel concentration: 12%.
Key Reference:
Kimura,K., (2006) Genome Res. 16 (1), 55-65
Reconstitution and Storage:
Add 100 ul of distilled water. Final anti-GCDH antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
 
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