FOXE1 Antibody - middle region (ARP31705_P050)

Catalog No: ARP31705_P050

WB Suggested Anti-FOXE1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Muscle

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Pig
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FOXE1
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: APATTTGYQPAGCTGARPANPSAYAAAYAGPDGAYPQGAGSAIFAAAGRL
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-FOXE1 (ARP31705_P050) antibody is Catalog # AAP31705 (Previous Catalog # AAPP23931)
• Reference: Carre,A., (2007) Hum. Genet. 122 (5), 467-476

Target Info

• Gene Symbol: FOXE1
• Gene Full Name: Forkhead box E1 (thyroid transcription factor 2)
• Alias Symbols: TTF2, FOXE2, HFKH4, HFKL5, NMTC4, TITF2, TTF-2, FKHL15
• NCBI Gene Id: 2304
• Protein Name: Forkhead box protein E1
• Description of Target: FOXE1 belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. It functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I.This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Uniprot ID: O00358
• Protein Accession #: NP_004464
• Nucleotide Accession #: NM_004473
• Protein Size (# AA): 373
• Molecular Weight: 38kDa
• Protein Interactions: PLCB3;