FKBP6 Antibody - middle region (ARP43027_T100)

Catalog No: ARP43027_T100

WB Suggested Anti-FKBP6 Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysate

Human kidney

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: IHC, WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FKBP6
• Purification: Protein A purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 77%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: FCALSAEQQDQFPLQKVLKVAATEREFGNYLFRQNRFYDAKVRYKRALLL
• Concentration: 1.0 mg/ml
• Blocking Peptide: For anti-FKBP6 (ARP43027_T100) antibody is Catalog # AAP43608 (Previous Catalog # AAPS13809)
• Reference: Ye,X.Q., (2005) Int. J. Mol. Med. 16 (5), 851-856

Target Info

• Gene Symbol: FKBP6
• Gene Full Name: FK506 binding protein 6, 36kDa
• Alias Symbols: FKBP36
• NCBI Gene Id: 8468
• Protein Name: Peptidyl-prolyl cis-trans isomerase FKBP6
• Description of Target: FKBP6 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP6 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin.This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.
• Uniprot ID: O75344
• Protein Accession #: NP_003593
• Nucleotide Accession #: NM_006147
• Protein Size (# AA): 467
• Molecular Weight: 53kDa
• Protein Interactions: LZTS2; CDK5RAP3; SUMO1P1; CCDC36; CDC37; USP19; PTGES3; VBP1; PFDN2; OSBP; HSP90AB1; HSP90AA1; TINF2; ACD; NME7; CCNK; GAPDH;