FCGR2B Antibody (OAAF00870)

Catalog No: OAAF00870 (Formerly GWB-ASC285)

Size:100 ug

Western blot analysis of extracts from 293/HepG2/HeLa cells, treated with PMA 125ng/ml 30', using CD32 Antibody. The lane on the right is treated with the synthesized peptide.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid
• Clonality: Polyclonal
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
• Reconstitution and Storage: -20°C
• Immunogen: The antiserum was produced against synthesized peptide derived from human CD32.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Specificity: CD32 (Ab-292) antibody detects endogenous levels of total CD32 protein
• Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Dilution: The optimal working dilution should be determined by the end user.
• Application Info: WB: 1:500~1:3000; ELISA: 1:1000
• Reference: Belen de Andrés. Blood, Aug 1997; 90: 1267 - 1274.
  M Groger. J. Immunol., Feb 1996; 156: 1549.
  Diana Metes. Blood, Apr 1998; 91: 2369 - 2380.
  Belen de Andres. Blood, Oct 1998; 92: 2823 - 2829

Target Info

• Gene Symbol: FCGR2B
• Gene Full Name: Fc fragment of IgG receptor IIb
• Alias Symbols: CD32;CD32B;CDw32;Fc fragment of IgG, low affinity II, receptor for (CD32);Fc fragment of IgG, low affinity IIb, receptor (CD32);Fc fragment of IgG, low affinity IIb, receptor for (CD32);Fc gamma receptor IIb;Fc gamma RIIb;FCG2;fc-gamma RII-b;Fc-gamma RII-c;fc-gamma-RIIb;Fc-gamma-RIIc;FCGR2;FCGR2C;fcRII-b;FcRII-c;IGFR2;igG Fc receptor II-b;IgG Fc receptor II-c;low affinity immunoglobulin gamma Fc region receptor II-b;Low affinity immunoglobulin gamma Fc region receptor II-c.
• NCBI Gene Id: 2213
• Protein Name: Low affinity immunoglobulin gamma Fc region receptor II-b
• Description of Target: Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
• Uniprot ID: P31994
• Protein Accession #: NP_001002273.1
• Molecular Weight: 34 kda