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Catalog No: ARP32264_P050
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ARP32264_P050
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ETV5 Antibody - N-terminal region (ARP32264_P050)

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Datasheets/ManualsPrintable datasheet for anti-ETV5 (ARP32264_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human ETV5
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
Peptide SequenceSynthetic peptide located within the following region: AQVPDDEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSSCSHEQALGA
Concentration0.5 mg/ml
Blocking PeptideFor anti-ETV5 (ARP32264_P050) antibody is Catalog # AAP32264 (Previous Catalog # AAPP03245)
ReferenceDegerny,C., (2005) J. Biol. Chem. 280 (26), 24330-24338
Gene SymbolETV5
Gene Full NameEts variant 5
Alias SymbolsERM
NCBI Gene Id2119
Protein NameETS translocation variant 5
Description of TargetETV5 Contains 1 ETS DNA-binding domain and belongs to the ETS family. The ETV5 gene expression is regulated by the conventional PKC (cPKC) pathway.ETV5 is subject to SUMO modification and this post-translational modification causes inhibition of transcription-enhancing activity Phosphorylated ETV5 and the actin cytoskeleton regulate CD44-mediated hyaluronan binding in myeloid cells. ERMs (ezrin/radixin/moesin) function as adaptor molecules in the interactions of adhesion receptors and intracellular tyrosine kinases. ETV5 can cooperate with c-Jun and has a role in progression of breast cancer
Uniprot IDP41161
Protein Accession #NP_004445
Nucleotide Accession #NM_004454
Protein Size (# AA)510
Molecular Weight58kDa
Protein InteractionsRFWD2; HDAC11; DHRS7; SEZ6L2; SLC22A2; HOXD9; CYP3A5; CCR5; CISH; AMH; APP; BRCA1; ELAVL1; SUMO2; UBC; AR;
  1. What is the species homology for "ETV5 Antibody - N-terminal region (ARP32264_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".

  2. How long will it take to receive "ETV5 Antibody - N-terminal region (ARP32264_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "ETV5 Antibody - N-terminal region (ARP32264_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ETV5 Antibody - N-terminal region (ARP32264_P050)"?

    This target may also be called "ERM" in publications.

  5. What is the shipping cost for "ETV5 Antibody - N-terminal region (ARP32264_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ETV5 Antibody - N-terminal region (ARP32264_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ETV5 Antibody - N-terminal region (ARP32264_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "58kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ETV5 Antibody - N-terminal region (ARP32264_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ETV5"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ETV5"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ETV5"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ETV5"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ETV5"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ETV5"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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