Catalog No: OABF00702
Size:100UL
Price: $438.00
SKU
OABF00702
Availability: 3 to 5 business days.
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for EPAS1 Antibody (OABF00702)
Product Info
Predicted Species ReactivityBovine|Horse|Human|Monkey|Mouse|Porcine|Rat|Sheep
Product FormatLiquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationEnzyme-linked immunosorbent assay|Flow cytometry|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot
Additional InformationSubcellular location: Nucleus
Reconstitution and Storage-20°C
ImmunogenKLH conjugated synthetic peptide derived from mouse HIF2 Alpha
PurificationProtein A Purified
Concentration1 ug/ul
Application InfoWB: 1:100 - 1000
IHC-P: : 1:100 - 500
Gene SymbolEpas1
Gene Full Nameendothelial PAS domain protein 1
Alias SymbolsbHLHe7;bHLHe73;endothelial PAS domain-containing protein 1;EPAS-1;HIF;Hif like protein;HIF1 alpha-like factor;HIF1alpha-like factor;HIF-1-alpha-like factor;HIF-2;HIF2A;HIF2-alpha;HIF-2alpha;HIF-2-alpha;HIF-related factor;HL;HLF;HLF (HIF1alpha-like factor);HR;HRF;hypoxia inducible transcription factor 2alpha;hypoxia-inducible factor 2-alpha;mHLF;MO;MOP2.
NCBI Gene Id13819
Protein NameEndothelial PAS domain-containing protein 1
Description of TargetTranscription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters (PubMed:26245371). Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD (By similarity).
Uniprot IDP97481
  1. What is the species homology for "EPAS1 Antibody (OABF00702)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Bovine|Horse|Human|Monkey|Mouse|Porcine|Rat|Sheep".

  2. How long will it take to receive "EPAS1 Antibody (OABF00702)"?

    This item is available "3 to 5 business days.".

  3. What buffer format is "EPAS1 Antibody (OABF00702)" provided in?

    This item is provided in "Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "EPAS1 Antibody (OABF00702)"?

    This target may also be called "bHLHe7;bHLHe73;endothelial PAS domain-containing protein 1;EPAS-1;HIF;Hif like protein;HIF1 alpha-like factor;HIF1alpha-like factor;HIF-1-alpha-like factor;HIF-2;HIF2A;HIF2-alpha;HIF-2alpha;HIF-2-alpha;HIF-related factor;HL;HLF;HLF (HIF1alpha-like factor);HR;HRF;hypoxia inducible transcription factor 2alpha;hypoxia-inducible factor 2-alpha;mHLF;MO;MOP2." in publications.

  5. What is the shipping cost for "EPAS1 Antibody (OABF00702)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "EPAS1 Antibody (OABF00702)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "EPAS1 Antibody (OABF00702)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "EPAS1 Antibody (OABF00702)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "Epas1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "Epas1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "Epas1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "Epas1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "Epas1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "Epas1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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