Catalog No: ARP31639_P050
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ARP31639_P050
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Datasheets/ManualsPrintable datasheet for anti-Elf3 (ARP31639_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Cow, Dog, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human Elf3
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 86%; Dog: 79%; Horse: 92%; Human: 100%; Pig: 93%; Rabbit: 100%
Peptide SequenceSynthetic peptide located within the following region: GSCGAGAPSPGSSDVSTAGTGASRSSHSSDSGGSDVDLDPTDGKLFPSDG
Concentration0.5 mg/ml
Blocking PeptideFor anti-Elf3 (ARP31639_P050) antibody is Catalog # AAP31639 (Previous Catalog # AAPP02426)
Sample Type Confirmation

Elf3 is supported by BioGPS gene expression data to be expressed in MCF7

ReferencePeng,H., (2008) J. Cell. Physiol. 215 (2), 562-573
Gene SymbolElf3
Gene Full NameE74-like factor 3 (ets domain transcription factor, epithelial-specific )
Alias SymbolsERT, ESX, EPR-1, ESE-1
NCBI Gene Id1999
Protein NameETS-related transcription factor Elf-3
Description of TargetELF3 is a novel, highly tissue-restricted member of the ets transcription factor/oncogene family. ELF3 contains two putative DNA binding domains: an ETS domain, which is unique in that the 5' half shows relatively weak homology to known ets factors, and an A/T hook domain, found in HMG proteins and various other nuclear factors. In contrast to any known ets factors, ELF3 is expressed exclusively in epithelial cells. ELF3 is expected to be a critical regulator of epithelial cell differentiation. ETS factor ELF3 is a transcriptional regulator of angiopoietin-1 gene regulation in the setting of inflammation. ELF3 overexpressed early during human breast tumorigenesis. ELF3 expression confers a transformed and in vitro metastatic phenotype to otherwise normal MCF-12A cells. ELF3 mediates the expression of TGF-beta RII, and the transcriptional inhibition of ets-related transcription factor could be a one of the mechanisms of colonic carcinogenesis. ELF3 is positively and negatively modulated by other interacting proteins including Ku70, Ku86, p300, and CBP.
Uniprot IDP78545
Protein Accession #NP_004424
Nucleotide Accession #NM_004433
Protein Size (# AA)371
Molecular Weight41kDa
Protein InteractionsMED23; XRCC5; RPL6; XRCC6; EP300; CBR3; Jun; MYC; BTRC; UBC; PAK1; TAF9; SUMO2; TBP; EPS15; CREBBP; NFKB1; EGFR; ERBB2; EHF; GANAB; ISG15; TARS; P4HB; KRT82; KRT31; JAK1; EEF1D; DDX3X; CALR; ATIC;
  1. What is the species homology for "Elf3 Antibody - middle region (ARP31639_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Cow, Dog, Horse, Pig, Rabbit".

  2. How long will it take to receive "Elf3 Antibody - middle region (ARP31639_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "Elf3 Antibody - middle region (ARP31639_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Elf3 Antibody - middle region (ARP31639_P050)"?

    This target may also be called "ERT, ESX, EPR-1, ESE-1" in publications.

  5. What is the shipping cost for "Elf3 Antibody - middle region (ARP31639_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Elf3 Antibody - middle region (ARP31639_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Elf3 Antibody - middle region (ARP31639_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "41kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Elf3 Antibody - middle region (ARP31639_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ELF3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ELF3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ELF3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ELF3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ELF3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ELF3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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