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Datasheets/Manuals | Printable datasheet for DR3 Antibody (OAPB00028) (OAPB00028) |
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Predicted Species Reactivity | Human|Mouse |
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Product Format | Liquid. DR3 Antibody is supplied in PBS containing 0.02% sodium azide. |
Clonality | Polyclonal |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot |
:: | Buffer: Antibody is supplied in PBS containing 0.02% sodium azide. |
Reconstitution and Storage | DR3 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Immunogen | DR3 antibody was raised against a peptide corresponding to amino acids in extracellular domain of human DR3 precusor. The immunogen is located within amino acids 50 - 100 of DR3. |
Purification | Ion Exchange |
Predicted Homology Based on Immunogen Sequence | Human; Mouse |
Concentration | 1 mg/ml |
Blocking Peptide | For anti-DR3 antibody is Catalog # OEPB02156 |
Application Info | DR3 antibody can be used for detection of DR3 expression by Western blot at 1:500 to 1:1000 dilution. 59 kDa band should be detected. (Optimal dilution should be determined by user) |
Reference | Chinnaiyan AM; O'Rourke K; Yu GL; Lyons RH; Garg M; Duan DR; Xing L; Gentz R; Ni J; Dixit VM. Science, 1996;274:990-2.;Kitson J; Raven T; Jiang YP; Goeddel DV; Giles KM; Pun KT; Grinham CJ; Brown R; Farrow SN. Nature, 1996;384:372-5. ;Marsters SA; Sheridan JP; Donahue CJ; Pitti RM; Gray CL; Goddard AD; Bauer KD; Ashkenazi A. Curr Biol, 1996;6:1669-76.;Bodmer JL; Burns K; Schneider P; Hofmann K; Steiner V; Thome M; Bornand T; Hahne M; Schroter M; Becker K; et al. Immunity, 1997;6:79-88. |
Gene Symbol | TNFRSF25 |
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Gene Full Name | TNF receptor superfamily member 25 |
Alias Symbols | APO-3;apoptosis inducing receptor;apoptosis-inducing receptor AIR;apoptosis-mediating receptor DR3;apoptosis-mediating receptor TRAMP;DDR3;death domain receptor 3 soluble form;Death receptor 3;death receptor beta;DR3;GEF720;Guanine nucleotide exchange factor 720;LARD;lymphocyte-associated receptor of death;PH domain-containing family G member 5;Pleckstrin homology domain-containing family G member 5;PLEKHG5;Protein WSL;protein WSL-1;TNFRSF12;TR3;TRAMP;tumor necrosis factor receptor superfamily member 25;tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein);WSL-1;WSL-LR. |
NCBI Gene Id | 8718 |
Protein Name | DR3 [Homo sapiens]|Tumor necrosis factor receptor superfamily member 25 |
Description of Target | Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. |
Uniprot ID | Q93038 |
Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/AAQ88676 |
Molecular Weight | 59 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "DR3 Antibody (OAPB00028)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
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How long will it take to receive "DR3 Antibody (OAPB00028)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "DR3 Antibody (OAPB00028)" provided in?
This item is provided in "Liquid. DR3 Antibody is supplied in PBS containing 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "DR3 Antibody (OAPB00028)"?
This target may also be called "APO-3;apoptosis inducing receptor;apoptosis-inducing receptor AIR;apoptosis-mediating receptor DR3;apoptosis-mediating receptor TRAMP;DDR3;death domain receptor 3 soluble form;Death receptor 3;death receptor beta;DR3;GEF720;Guanine nucleotide exchange factor 720;LARD;lymphocyte-associated receptor of death;PH domain-containing family G member 5;Pleckstrin homology domain-containing family G member 5;PLEKHG5;Protein WSL;protein WSL-1;TNFRSF12;TR3;TRAMP;tumor necrosis factor receptor superfamily member 25;tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein);WSL-1;WSL-LR." in publications.
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What is the shipping cost for "DR3 Antibody (OAPB00028)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "DR3 Antibody (OAPB00028)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "DR3 Antibody (OAPB00028)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "59 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "DR3 Antibody (OAPB00028)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "TNFRSF25"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "TNFRSF25"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "TNFRSF25"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "TNFRSF25"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "TNFRSF25"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "TNFRSF25"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.