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- $55: Antibody & Protein in US
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Datasheets/Manuals | Printable datasheet for DOK1 Antibody (OAAF01278) |
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Predicted Species Reactivity | Human|Mouse|Rat |
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Product Format | Liquid |
Clonality | Polyclonal |
Host | Rabbit |
Application | Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot |
Reconstitution and Storage | -20°C |
Immunogen | The antiserum was produced against synthesized peptide derived from human p62 Dok. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Specificity | p62Dok (Ab-398) antibody detects endogenous levels of total p62Dok protein. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Dilution | The optimal working dilution should be determined by the end user. |
Application Info | WB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:20000 |
Reference | Michael J. Wick, et,al. (2001) J. Biol. Chem; 276: 42843-42850. Paul D. Simoncic, et,al. (2006) Mol. Cell. Biol; 26: 4149-4160. Nadia Dubé, et,al. (2004) PNAS; 101: 1834. Adam C. Yopp, et al. (2005) J. Immunol; 175: 2913-2924. |
Gene Symbol | DOK1 |
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Gene Full Name | docking protein 1 |
Alias Symbols | docking protein 1;Downstream of tyrosine kinase 1;p62(dok);P62DOK;pp62. |
NCBI Gene Id | 1796 |
Protein Name | Docking protein 1 |
Description of Target | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3. |
Uniprot ID | Q99704 |
Protein Accession # | NP_001184189.1 |
Molecular Weight | 52 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "DOK1 Antibody (OAAF01278)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".
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How long will it take to receive "DOK1 Antibody (OAAF01278)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "DOK1 Antibody (OAAF01278)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "DOK1 Antibody (OAAF01278)"?
This target may also be called "docking protein 1;Downstream of tyrosine kinase 1;p62(dok);P62DOK;pp62." in publications.
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What is the shipping cost for "DOK1 Antibody (OAAF01278)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "DOK1 Antibody (OAAF01278)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "DOK1 Antibody (OAAF01278)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "52 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "DOK1 Antibody (OAAF01278)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "DOK1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "DOK1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "DOK1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "DOK1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "DOK1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "DOK1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.