DISC1 Antibody - N-terminal region (OAGA02699)

Catalog No: OAGA02699

Size:100 ul

Sample (30 ug of whole cell lysate)
A:MOLT4 7.5% SDS PAGE
OAGA02699 diluted at 1:1500

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human DISC1. The exact sequence is proprietary.
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 1mg/ml
• Application Info: Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Target Info

• Gene Symbol: DISC1
• Gene Full Name: disrupted in schizophrenia 1
• Alias Symbols: SCZD9, C1orf136
• NCBI Gene Id: 27185
• Description of Target: This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Uniprot ID: Q9NRI5