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Catalog No: OAAN00178
Price: $0.00
SKU
OAAN00178
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for anti-DFFA (OAAN00178)
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationWB, IHC, IF
Reconstitution and StorageStore at -20C. Avoid repeated freeze/thaw cycles.
ImmunogenRecombinant protein of human DFFA
PurificationAffinity purified against immunogen
Preservative0.02% Sodium Azide
Application InfoWB: 1:500 - 1:2,000. IHC: 1:50 - 1:200. IF: 1:50 - 1:100
Storage BufferPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene SymbolDFFA
Gene Full NameDNA fragmentation factor subunit alpha
Alias SymbolsDFF1, ICAD, DFF-45
NCBI Gene Id1676
Protein NameDNA fragmentation factor subunit alpha
Description of TargetApoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Uniprot IDO00273
Protein Accession #NP_004392.1
Nucleotide Accession #NM_004401.2
Molecular Weight37 kDa
  1. What is the species homology for "DFFA Antibody (OAAN00178)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "DFFA Antibody (OAAN00178)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "DFFA Antibody (OAAN00178)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "DFFA Antibody (OAAN00178)"?

    This target may also be called "DFF1, ICAD, DFF-45" in publications.

  5. What is the shipping cost for "DFFA Antibody (OAAN00178)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "DFFA Antibody (OAAN00178)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "DFFA Antibody (OAAN00178)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "37 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "DFFA Antibody (OAAN00178)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "DFFA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "DFFA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "DFFA"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "DFFA"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "DFFA"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "DFFA"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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