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Datasheets/Manuals | Printable datasheet for DC-SIGN Antibody (OAPB01326) (OAPB01326) |
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Predicted Species Reactivity | Human |
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Product Format | Liquid. DC-SIGN Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide. |
Clonality | Monoclonal |
Host | DC-SIGN monoclonal antibody was raised in mouse. Please use anti-mouse secondary antibodies. |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunohistochemistry-Paraffin|Western blot |
Additional Information | Human Uterus Tissue Lysate (OCPB00088), Human Lymph Node Tissue Lysate (OCPB00102) |
:: | Buffer: Antibody is supplied in PBS containing 0.02% sodium azide. |
Reconstitution and Storage | DC-SIGN monoclonal antibody can be stored at 4C, stable for one year. |
Immunogen | A recombinant His-tagged protein fragment corresponding to the extracellular region of human DC-SIGN. |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Human |
Concentration | 1 mg/ml |
Application Info | DC-SIGN antibody can be used for detection of DC-SIGN in immunoblots at 1 – 2 mg/ml and in immunohistochemistry at 5 – 10 mg/ml. (Optimal dilution should be determined by user) |
Reference | Geijtenbeek TB, Kwon DS, Torensma R, et al. DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell 2000; 100:587-97. ;Pohlmann S, Baribaud F, Lee B, et al. DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus. J. Virol. 2001;75:4664-72. ;Geijtenbeek TB, Torensma R, van Vliet SJ, et al. Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses. Cell 2000; 100:575-85. ;Soilleux EJ, Barten R, Trowsdale J. DC-SIGN; a related gene, DC-SIGNR; and CD23 form a cluster on 19p13. J. Immunol. 2000; 165:2937-42. extensive repertoire of membrane-bound and soluble DC-SIGN1 and DC-SIGN2 isoforms: Inter-individual variation in expression of DC-SIGN transcripts. J Biol Chem. 2001; 276:33196-212. |
Gene Symbol | CD209 |
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Gene Full Name | CD209 molecule |
Alias Symbols | CD209 antigen;CDSIGN;CLEC4L;C-type lectin domain family 4 member L;DC-SIGN;DC-SIGN1;dendritic cell-specific ICAM-3-grabbing non-integrin 1;dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin;dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin;hDC-SIGN;HIV gpl20-binding protein. |
NCBI Gene Id | 30835 |
Protein Name | CD209 antigen |
Description of Target | Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. |
Uniprot ID | Q9NNX6 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "DC-SIGN Antibody (OAPB01326)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "DC-SIGN Antibody (OAPB01326)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "DC-SIGN Antibody (OAPB01326)" provided in?
This item is provided in "Liquid. DC-SIGN Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "DC-SIGN Antibody (OAPB01326)"?
This target may also be called "CD209 antigen;CDSIGN;CLEC4L;C-type lectin domain family 4 member L;DC-SIGN;DC-SIGN1;dendritic cell-specific ICAM-3-grabbing non-integrin 1;dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin;dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin;hDC-SIGN;HIV gpl20-binding protein." in publications.
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What is the shipping cost for "DC-SIGN Antibody (OAPB01326)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "DC-SIGN Antibody (OAPB01326)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "DC-SIGN Antibody (OAPB01326)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "DC-SIGN Antibody (OAPB01326)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CD209"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CD209"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CD209"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CD209"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CD209"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CD209"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.