CYBB Recombinant Protein (OPCD02586)

Catalog No: OPCD02586

CYBB Recombinant Protein (OPCD02586) using SDS-PAGE

CYBB Recombinant Protein (OPCD02586) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Isoelectric Point: 7.3
  Residues: Glu283-Phe570
  Subcellular Location: Cell membrane; Multi-pass membrane protein
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: CYBB
• Gene Full Name: cytochrome b-245 beta chain
• Alias Symbols: AMCBX2;CGD;CGD91-phox;CGDX;cytochrome b(558) subunit beta;cytochrome b-245 beta polypeptide;cytochrome b-245 heavy chain;cytochrome b558 subunit beta;GP91-1;GP91PHOX;GP91-PHOX;heme-binding membrane glycoprotein gp91phox;IMD34;NADPH oxidase 2;neutrophil cytochrome b 91 kDa polypeptide;NOX2;p22 phagocyte B-cytochrome;p91-PHOX;superoxide-generating NADPH oxidase heavy chain subunit.
• NCBI Gene Id: 1536
• Protein Name: Cytochrome b-245 heavy chain
• Description of Target: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.
• Uniprot ID: P04839
• Protein Accession #: NP_000388.2
• Nucleotide Accession #: NM_000397.3
• Protein Size (# AA): Glu283~Phe570
• Molecular Weight: 35kDa