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Catalog No: OAAF01839 (Formerly GWB-ASD110)
Size:100 ug
Price: $344.00
SKU
OAAF01839
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for COPS3 Antibody (OAAF01839)
Product Info
Predicted Species ReactivityHuman|Mouse|Rat
Product FormatLiquid
ClonalityPolyclonal
HostRabbit
ApplicationEnzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Reconstitution and Storage-20°C
ImmunogenThe antiserum was produced against synthesized peptide derived from human JAB1.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
SpecificityJAB1 antibody detects endogenous levels of total JAB1 protein.
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
DilutionThe optimal working dilution should be determined by the end user.
Application InfoWB: 1:500~1:3000; IF: 1:100~1:500; ELISA: 1:5000
ReferenceGeorge Z. Rassidakis, Clin. Cancer Res., Mar 2003; 9: 1121.
Ricardo V. Lloyd, Am. J. Pathol., Mar 2002; 160: 1171.
Shu Xiao, PNAS, Oct 2006; 103: 16448 - 16453.
Alex Kudrin, J. Biol. Chem., Oct 2006; 281: 29641 - 29651.
Gene SymbolCOPS3
Gene Full NameCOP9 signalosome subunit 3
Alias SymbolsCOP9 complex subunit 3;COP9 constitutive photomorphogenic homolog subunit 3;COP9 signalosome complex subunit 3;CSN3;JAB1-containing signalosome subunit 3;SGN3;signalosome subunit 3.
NCBI Gene Id8533
Protein NameCOP9 signalosome complex subunit 3
Description of TargetComponent of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
Uniprot IDQ9UNS2
Protein Accession #NP_001186054.1
Molecular Weight47 kDa
  1. What is the species homology for "COPS3 Antibody (OAAF01839)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".

  2. How long will it take to receive "COPS3 Antibody (OAAF01839)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "COPS3 Antibody (OAAF01839)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "COPS3 Antibody (OAAF01839)"?

    This target may also be called "COP9 complex subunit 3;COP9 constitutive photomorphogenic homolog subunit 3;COP9 signalosome complex subunit 3;CSN3;JAB1-containing signalosome subunit 3;SGN3;signalosome subunit 3." in publications.

  5. What is the shipping cost for "COPS3 Antibody (OAAF01839)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "COPS3 Antibody (OAAF01839)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "COPS3 Antibody (OAAF01839)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "47 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "COPS3 Antibody (OAAF01839)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "COPS3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "COPS3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "COPS3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "COPS3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "COPS3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "COPS3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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