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CACNB2(calcium channel, voltage-dependent, beta 2 subunit) Antibody


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Catalog#   Accession # Size Price Qty
ARP35594_P050   NP_963866 50µg $289.00
Description: 
CACNB2 belongs to the calcium channel beta subunit family.The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.Defects in CACNB2 are the cause of Brugada syndrome type 4 (BRS4).
Gene Symbol: 
CACNB2  
Alias Symbols: 
CACNLB2; FLJ23743; MYSB  
Peptide ID: 
P23773  
ELISA titre using peptide based assay: 
1:312500  
Search Keyword: 
CACNB2, CACNLB2; FLJ23743; MYSB, NP_963866  
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Species Reactivity: 
(Primary - WB; Secondary - Computational Homology)
Human 
Antigen Specificity: 
Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human CACNB2 with an internal ID of P23773 
Reconstitution and Storage: 
Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 μl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. 
Key Reference: 
Uhl,G.R., (2008) Arch. Gen. Psychiatry 65 (6), 683-693 
Quality Control: 
Rabbit Ig G is purified by peptide affinity chromatography method. 
Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. For research use only not for diagnostic, human, or veterinary use.
Western Blot
Suggested dilution at 1µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.
Immunoblot

ARP35594-QC11688-WB.jpg
 
Protein Accession# Swissprot Id Nucleotide Accession# Protein Size Molecular Weight
NP_963866 A6PVM7 NM_201572 608 68kDa