Catalog No: ARP42396_T100
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ARP42396_T100
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Datasheets/ManualsPrintable datasheet for anti-CLEC4M (ARP42396_T100) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Pig
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human CLEC4M
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceHuman: 100%; Pig: 86%
Peptide SequenceSynthetic peptide located within the following region: LVLQLLSFMLLAGVLVAILVQVSKVPSSLSQEQSEQDAIYQNLTQLKAAV
Concentration1.0 mg/ml
Blocking PeptideFor anti-CLEC4M (ARP42396_T100) antibody is Catalog # AAP42396 (Previous Catalog # AAPP24747)
ReferenceLiu,H., (2006) J. Infect. Dis. 193 (5), 698-702
Gene SymbolCLEC4M
Gene Full NameC-type lectin domain family 4, member M
Alias SymbolsCD299, LSIGN, CD209L, L-SIGN, DCSIGNR, HP10347, DC-SIGN2, DC-SIGNR
NCBI Gene Id10332
Protein NameC-type lectin domain family 4 member M
Description of TargetCLEC4M is a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
Uniprot IDQ9H2X3
Protein Accession #NP_055072
Nucleotide Accession #NM_014257
Protein Size (# AA)399
Molecular Weight44kDa
Protein InteractionsTLR2; MME; CLEC4M; CD209; ICAM3; ITGAM; AP2M1; HCVgp1;
  1. What is the species homology for "CLEC4M Antibody - N-terminal region (ARP42396_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Pig".

  2. How long will it take to receive "CLEC4M Antibody - N-terminal region (ARP42396_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "CLEC4M Antibody - N-terminal region (ARP42396_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CLEC4M Antibody - N-terminal region (ARP42396_T100)"?

    This target may also be called "CD299, LSIGN, CD209L, L-SIGN, DCSIGNR, HP10347, DC-SIGN2, DC-SIGNR" in publications.

  5. What is the shipping cost for "CLEC4M Antibody - N-terminal region (ARP42396_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CLEC4M Antibody - N-terminal region (ARP42396_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CLEC4M Antibody - N-terminal region (ARP42396_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "44kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CLEC4M Antibody - N-terminal region (ARP42396_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CLEC4M"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CLEC4M"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CLEC4M"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CLEC4M"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CLEC4M"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CLEC4M"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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