Catalog No: ANA00002-P001
Size:1ug
Price: $209.00
SKU
ANA00002-P001
Availability: Domestic: within 24 hours delivery | International: 3-5 days
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Datasheets/Manuals | Printable datasheet for anti-CDK9 (ANA00002-P001) antibody |
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Reconstitution and Storage | Already in solution (1 ug/ul). For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
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Tag | None |
Reference | Li,Q., (2005) J. Biol. Chem. 280 (31), 28819-28826 |
Gene Symbol | CDK9 |
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Alias Symbols | TAK, C-2k, CTK1, CDC2L4, PITALRE |
NCBI Gene Id | 1025 |
Protein Name | Cyclin-dependent kinase 9 |
Description of Target | CDK9 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. |
Uniprot ID | P50750 |
Protein Accession # | NP_001252 |
Nucleotide Accession # | NM_001261 |
Protein Interactions | UBC; MEPCE; tat; LARP7; BRD4; CCNT1; ATM; SUMO2; AFF1; HEXIM1; FKBP5; RNF20; MSL2; RNF40; HIST2H2BE; POLR2A; MSL1; CDK9; SMC2; PLEC; CCAR2; SMC4; STIP1; MLLT3; MLLT1; CDK12; AFF4; FGFR1; CCNT2; AFF3; FBXO25; CUL1; SKIV2L; ATP1A1; SUPT5H; RPS4X; RN7SK; HEX |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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