Catalog No: ANA00002-P001
Size:1ug
Price: $209.00
SKU
ANA00002-P001
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CDK9 cDNA (ANA00002-P001)

Datasheets/ManualsPrintable datasheet for anti-CDK9 (ANA00002-P001) antibody
Product Info
Reconstitution and StorageAlready in solution (1 ug/ul). For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
TagNone
ReferenceLi,Q., (2005) J. Biol. Chem. 280 (31), 28819-28826
Gene SymbolCDK9
Alias SymbolsTAK, C-2k, CTK1, CDC2L4, PITALRE
NCBI Gene Id1025
Protein NameCyclin-dependent kinase 9
Description of TargetCDK9 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
Uniprot IDP50750
Protein Accession #NP_001252
Nucleotide Accession #NM_001261
Protein InteractionsUBC; MEPCE; tat; LARP7; BRD4; CCNT1; ATM; SUMO2; AFF1; HEXIM1; FKBP5; RNF20; MSL2; RNF40; HIST2H2BE; POLR2A; MSL1; CDK9; SMC2; PLEC; CCAR2; SMC4; STIP1; MLLT3; MLLT1; CDK12; AFF4; FGFR1; CCNT2; AFF3; FBXO25; CUL1; SKIV2L; ATP1A1; SUPT5H; RPS4X; RN7SK; HEX
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