CDC25C Antibody (OAAD00133)

Catalog No: OAAD00133

Size:100 ug

Product Info

• Predicted Species Reactivity: Human
• Clonality: Monoclonal
• Clone: IMD-25
• Isotype: IgG1
• Host: Mouse
• Application: WB
• Reconstitution and Storage: At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for longer time.
• Immunogen: Recombinant human Cdc25c.
• Purification: Purified by the goat anti-mouse IgG Affinity chromatography.
• Specificity: Human.
  No cross reactivity with other proteins.
• Formulation: Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.01mg NaN3 as preservative.
• Application Info: Western blot At 1-2ug/ml with the appropriate system to detect cdc25c in cells and tissues.
  Other applications have not been tested.
  Optimal dilutions should be determined by end user.
• Storage Buffer: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
• Reference: 1. Sartor, H.; Ehlert, F.; Grzeschik, K.-H.; Muller, R.; Adolph, S. : Assignment of two human cell cycle genes, CDC25C and CCNB1, to 5q31 and 5q12, respectively. Genomics 13: 911-912, 1992.
  2. Taviaux, S. A.; Demaille, J. G. : Localization of human cell cycle regulatory genes CDC25C to 5q31 and WEE1 to 11p15.3-11p.15.1 by fluorescence in situ hybridization. Genomics 15: 194-196, 1993.

Target Info

• Gene Symbol: CDC25C
• Alias Symbols: CDC25, PPP1R60
• NCBI Gene Id: 995
• Protein Name: M-phase inducer phosphatase 3
• Description of Target: Cell division sycle(CDC25) gene product is a protein-tyrosine phosphatase, activates a partially purified p34(cdc2)/cyclin B complex. The cdc25 protein also shares homology with a protein phosphatase with activity against both tyrosine and serine (and thus probably threonine) phosphate residues. CDC25C is expressed predominantly in G2 phase in healer cells. The human gene encodes a protein with a predicted molecular mass of 53, 000 daltons whose C-terminal domain shares about 37% sequence identity with the fission yeast cdc25 mitotic inducer. CDC25C gene is mapped to 5q31.
• Uniprot ID: P30307