- Description of Target:
- CDC25C gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
- Gene Symbol:
- CDC25C
- Official Gene Full Name:
- Cell division cycle 25 homolog C (S. pombe)
- Alias Symbols:
- CDC25; PPP1R60
- Tissue Tool:
- Find tissues and cell lines supported to express CDC25C.
- Protein Accession# :
- NP_073720
- Nucleotide Accession#:
- NM_022809
- Swissprot Id:
- P30307
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Protein Size (# AA):
- 400
- Molecular Weight:
- 45kDa
- Application:
- WB
- Partner Proteins:
- CAND1, COMMD1, GPS1, NEDD8, RNF7, TCEB1, VHL, ZER1, ZYG11B, ASB4, CAB39, CAND1, CMBL, COMMD1, COPS5, COPS6, DCUN1D1, DLG3, HIF1A, KCTD5, NEDD8, P4HB, PFKFB3, RBX1, RNF7, RNMTL1, RPL35P5, Rbx1, SAP130, STOM, Socs1, TCEAL1, TCEB1, TCEB2, TFE3, TIMM13, VHL, Wsb1
- Immunogen:
- The immunogen for anti-CDC25C antibody: synthetic peptide directed towards the N terminal of human CDC25C
- Product Format:
- Lyophilized powder
- Purification:
- Affinity Purified
- Complete computational species homology data:
- CDC25C antibody - N-terminal region (AVARP03034_P050)
- Predicted Homology Based on Immunogen Sequence:
- Human: 100%; Mouse: 91%; Rabbit: 83%
- Datasheets / Downloads:
- Printable datasheet for
anti-CDC25C antibody
- AVARP03034_P050 - Peptide Sequence:
- Synthetic peptide located within the following region: QKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALRE
- Blocking Peptide:
- For anti-CDC25C antibody is Catalog # AAP30150 (Previous Catalog # AAPP00307)
- Key Reference:
- Bonnet,J., (2008) Biochem. Biophys. Res. Commun. 370 (3), 483-488
- Reconstitution and Storage:
- Add 50 μl of distilled water. Final anti-CDC25C antibody concentration is 1 mg/ml in PBS buffer. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Product Protocols: CDC25C antibody tested with Human Jurkat Cells (AVARP03034_P050)
Aviva Systems Biology is the original manufacturer of this CDC25C antibody (AVARP03034_P050)
Click here to view the CDC25C antibody Western Blot Protocol
Product Datasheet Link: CDC25C antibody (AVARP03034_P050)
WB Suggested Anti-CDC25C Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat
Western Blot image: 
Description of Target: CDC25C gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
Questions pertaining to this data can be directed to techsupport@avivasysbio.com
Aviva Systems Biology’s CDC25C antibody (AVARP03034_P050) has been tested using other cell lysates and tissues. To obtain more data about this antibody please email us at info@avivasysbio.com.
To order by phone call us at (888) 880-0001, fax us at (858) 552-6975 or send an email to info@avivasysbio.com. Aviva manufactures this antibody so we can offer the best price. Please contact us to request pricing information.
All of Aviva’s products are guaranteed for the applications and experimental sample types mentioned in the datasheet below. Are you curious if this product will work for you? Please contact us at techsupport@avivasysbio.com
- Protocol:
- Tips Information:
See our General FAQ page.
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