Catalog No: ARP43040_P050
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ARP43040_P050
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Datasheets/ManualsPrintable datasheet for anti-CDC23 (ARP43040_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human CDC23
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: DTREEGKALLRQILQLRNQGETPTTEVPAPFFLPASLSANNTPTRRVSPL
Concentration0.5 mg/ml
Blocking PeptideFor anti-CDC23 (ARP43040_P050) antibody is Catalog # AAP43040 (Previous Catalog # AAPP11247)
Sample Type Confirmation

CDC23 is supported by BioGPS gene expression data to be expressed in Jurkat

ReferenceBeausoleil,S.A., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135
Gene SymbolCDC23
Gene Full NameCell division cycle 23 homolog (S. cerevisiae)
Alias SymbolsAPC8, CUT23, ANAPC8
NCBI Gene Id8697
Protein NameCell division cycle protein 23 homolog
Description of TargetCDC23 shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
Uniprot IDQ9UJX2
Protein Accession #NP_004652
Nucleotide Accession #NM_004661
Protein Size (# AA)591
Molecular Weight65kDa
Protein InteractionsCCDC36; DLX6-AS1; SPERT; KCTD6; FAM9B; CCDC24; SSX2IP; PNMA5; CRACR2A; LZTS2; ATRIP; INCA1; CEP44; SLC52A2; EIF5A2; BCAS3; CYB5R2; HEMK1; RSL24D1; RBM15B; ANAPC2; UBE2S; INPP5J; GORASP2; ANAPC13; RAD54B; RBPMS; OPTN; CDC23; APOL1; COIL; UBC; SOX5; SIAH1;
  1. What is the species homology for "CDC23 Antibody - C-terminal region (ARP43040_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit".

  2. How long will it take to receive "CDC23 Antibody - C-terminal region (ARP43040_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "CDC23 Antibody - C-terminal region (ARP43040_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CDC23 Antibody - C-terminal region (ARP43040_P050)"?

    This target may also be called "APC8, CUT23, ANAPC8" in publications.

  5. What is the shipping cost for "CDC23 Antibody - C-terminal region (ARP43040_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CDC23 Antibody - C-terminal region (ARP43040_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CDC23 Antibody - C-terminal region (ARP43040_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "65kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CDC23 Antibody - C-terminal region (ARP43040_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CDC23"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CDC23"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CDC23"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CDC23"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CDC23"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CDC23"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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