CD138 Antibody - Biotin Conjugated (OADB00060)

Catalog No: OADB00060

Size:1 mL

A typical staining pattern with the B-A38 monoclonal antibody of U266 cell line

Product Info

• Predicted Species Reactivity: Human
• Product Format: Lyophilized PBS with 5% BSA and 0.1% sodium azide
• Clonality: Monoclonal
• Clone: B-A38
• Isotype: IgG1
• Host: Mouse
• Conjugation: Biotin
• Application: IHC
  Hydridoma: Myeloma X63/AG.8653 x Balb/c spleen cells
• Reconstitution and Storage: Reconstitute with 1 mL of deionized water. Use 10 uL to label 10⁶ cells or 100 uL of whole blood. Stable at 2-8C for six months after reconstitution. For longer storage, freeze aliquots.
• Immunogen: U266 cell line
• Purification: Ion exchange chromatography
• Concentration: 100 tests/1mL
• Specificity: Recognises Syndecan-1, the heparan sulfate proteoglycan, a 65-70 kDa protein

Target Info

• Gene Symbol: CD138
• Gene Full Name: syndecan 1
• Alias Symbols: SDC, CD138, SYND1, syndecan
• NCBI Gene Id: 6382
• Protein Name: syndecan-1
• Description of Target: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
• Uniprot ID: P18827
• Protein Accession #: NP_001006947.1
• Nucleotide Accession #: NM_001006946.1
• Molecular Weight: 32 kDa