CD11a Antibody (OAPA00036)

Catalog No: OAPA00036 (Formerly GWB-84330F)

Size:500UG

Product Info

• Predicted Species Reactivity: Mouse
• Clonality: Monoclonal
• Clone: mCD11a.
• Isotype: Rat IgG2b.
• Host: Rat
• Additional Information: Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf LifeTwo years lyophilized, one month in solution at 4C.
  Antibody Properties: Staining and blocking antibody. For staining, use 10 ul/106 cells. This antibody will block signaling through the CD11a molecule. Titer for blocking should be determined by the investigator.
  Product Introduction: ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling.
• Reconstitution and Storage: Lyophilized: store at 4C. After reconstitution, if not intended for use within a month, aliquot and store at -20C.
• Immunogen: The immunogen for anti-CD11a antibody: enriched mouse peritoneal macrophages.
• Purity: Ion exchange column.

Target Info

• Gene Symbol: ITGAL
• Alias Symbols: CD11A, LFA-1, LFA1A
• NCBI Gene Id: 3683
• Protein Name: Integrin alpha-L
• Description of Target: Rat Anti Mouse CD11a
• Uniprot ID: P20701