BMP2K(BMP2 inducible kinase) Antibody

• Catalog#: ARP42483_T100
• Accession#: NP_060063
• Size: 100µg

Description: 
BMP2K is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. BMP2K is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation.This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene.

Species Reactivity:  Human,Dog   Gene Symbol:  BMP2K   Alias Symbols:  BIKE; DKFZp434K0614; DKFZp434P0116; HRIHFB2017   Peptide ID:  S12809   ELISA titre using peptide based assay:  1:312500   Search Keyword:  BMP2K, NM_017593, NP_060063, Q4W5H2, NM_198892, NP_942595, Q9NSY1   Click Here to view more information (protein size, molecular weight, etc)

Antigen Specificity:  Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human BMP2K with an internal ID of S12809  Reconstitution and Storage:  Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 μl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.  Key Reference:  Arikawa,T., (2004) J. Cell. Physiol. 200 (3), 400-406  Quality Control:  Rabbit IgG purified by protein A chromatography.  Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. For research use only not for diagnostic, human, or veterinary use.

Western Blot Suggested dilution at 5.0µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. Immunoblot ARP42483-QC17308-WB.jpg Immunohistochemistry 1 ARP42483-QC17308-IHC.jpg

 

Protein Accession#	Swissprot Id	Nucleotide Accession#	Protein Size	Molecular Weight
NP_060063	Q4W5H2	NM_017593	662	74kDa
NP_942595	Q9NSY1	NM_198892	1161	129kDa