CDH7(cadherin 7, type 2) Antibody

• Catalog#: ARP46435_P050
• Accession#: NP_004352
• Size: 50µg

Description: 
CDH7 is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures.This gene is a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures. Alternative splicing in the 5' UTR of this gene yields variant transcripts encoding the same protein.

Species Reactivity:  Human,Mouse,Rat,Dog,ZebraFish   Gene Symbol:  CDH7   Alias Symbols:  CDH7L1   Peptide ID:  S18301   ELISA titre using peptide based assay:  1:12500   Search Keyword:  CDH7, NM_004361, NP_004352, Q9ULB5, NM_004061, NP_004052, P55289, NM_004934, NP_004925, Q13634, NM_031891, NP_114097, Q9HBT6, NM_033646, NP_387450, Q9ULB5   Click Here to view more information (protein size, molecular weight, etc)

Antigen Specificity:  Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human CDH7 with an internal ID of S18301  Reconstitution and Storage:  Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 μl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.  Key Reference:  Moore,R., (2004) Oncogene 23 (40), 6726-6735  Quality Control:  Rabbit Ig G is purified by peptide affinity chromatography method.  Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. For research use only not for diagnostic, human, or veterinary use.

Western Blot Suggested dilution at 0.25µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. Immunoblot ARP46435-QC16359-WB.jpg

 

Protein Accession#	Swissprot Id	Nucleotide Accession#	Protein Size	Molecular Weight
NP_004352	Q9ULB5	NM_004361	785	82kDa
NP_004052	P55289	NM_004061	794	88kDa
NP_004925	Q13634	NM_004934	790	88kDa
NP_114097	Q9HBT6	NM_031891	801	89kDa
NP_387450	Q9ULB5	NM_033646	785	87kDa