BMP7(bone morphogenetic protein 7 (osteogenic protein 1)) Antibody

Preview

Catalog#

Accession #

Size

Price

Qty

ARP32329_T100

NP_001710

100µg

$229.00

Description:
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

Species Reactivity:
Human, Mouse, Rat, Dog

Gene Symbol:
BMP7

Alias Symbols:
OP-1

Peptide ID:
P03316

ELISA titre using peptide based assay:
1:1562500

Search Keyword:
BMP7(bone morphogenetic protein 7 (osteogenic protein 1)) Antibody, NM_001719, NP_001710, P18075

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Antigen Specificity:
Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human BMP7 with an internal ID of P03316

Reconstitution and Storage:
Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 μl of distilled water. Final antibody concentration is 2 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.

Key Reference:
Gregory,K.E., (2005) J. Biol. Chem. 280 (30), 27970-27980

Quality Control:
Rabbit IgG purified by protein A chromatography.

Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. For research use only not for diagnostic, human, or veterinary use.

Western Blot
Suggested dilution at 1.25µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.

Immunoblot

ARP32329-QC7380-WB.jpg

Immunohistochemistry 1

ARP32329-QC7380-IHC.jpg

Protein Accession#	Swissprot Id	Nucleotide Accession#	Protein Size	Molecular Weight
NP_001710	P18075	NM_001719	431	49kDa