Home > Products >  Antibodies
Home > Products >Antibodies :   Signaling Intermediates
Home > Products >Antibodies :   Transcription Regulators
Home > Products >  Transcription Factor Antibodies
Home > Products >Transcription Factor Antibodies :   Nuclear Receptor

NR1I3(nuclear receptor subfamily 1, group I, member 3) Antibody


Preview
Catalog#   Accession # Size Price Qty
ARP33674_T100   NP_005113 100µg $229.00
Description: 
NR1I3 is a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members.
Species Reactivity: 
Human  
Gene Symbol: 
NR1I3  
Alias Symbols: 
CAR, CAR-BETA, CAR-SV1, CAR-SV10, CAR-SV11, CAR-SV12, CAR-SV13, CAR-SV14, CAR-SV15, CAR-SV17, CAR-SV18, CAR-SV19, CAR-SV20, CAR-SV21, CAR-SV4, CAR-SV6, CAR-SV7, CAR-SV8, CAR-SV9, CAR1, MB67, MGC97144  
Peptide ID: 
S07902  
ELISA titre using peptide based assay: 
1:62500  
Click Here to view more information (protein size, molecular weight, etc)
Antigen Specificity: 
Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human NR1I3 with an internal ID of S07902 
Reconstitution and Storage: 
Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 μl of distilled water. Final antibody concentration is 2 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. 
Key Reference: 
Ferguson,S.S., (2005) Mol. Pharmacol. 68 (3), 747-757 
Quality Control: 
Rabbit IgG purified by protein A chromatography. 
Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. For research use only not for diagnostic, human, or veterinary use.
Western Blot
Suggested dilution at 1.25µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.
Immunoblot

ARP33674-QC11748-WB.jpg
 
Protein Accession# Swissprot Id Nucleotide Accession# Protein Size Molecular Weight
NP_005113 Q5VTW5 NM_005122 348 40kDa
NP_001070937 NM_001077469 340 38kDa
NP_001070938 NM_001077470 280 32kDa
NP_001070939 NM_001077471 309 35kDa
NP_001070940 NM_001077472 324 37kDa
NP_001070941 NM_001077473 315 36kDa
NP_001070942 NM_001077474 296 33kDa
NP_001070943 NM_001077475 267 30kDa
NP_001070944 NM_001077476 311 35kDa
NP_001070945 NM_001077477 306 35kDa
NP_001070946 NM_001077478 339 38kDa
NP_001070947 NM_001077479 319 36kDa
NP_001070948 NM_001077480 352 40kDa
NP_001070949 NM_001077481 314 36kDa
NP_001070950 NM_001077482 357 40kDa