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ADARB1 (adenosine deaminase, RNA-specific, B1 (RED1 homolog rat)) Antibody

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Catalog#   Accession # Size Price Qty
ARP40342_T100   NP_001103 100µg $229.00
Description: 
ADARB1 is an enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site.This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.
Species Reactivity: 
Human, Mouse, Rat  
Gene Symbol: 
ADARB1  
Alias_Symbols: 
HGNC:226, ADAR2, DRABA2, DRADA2, RED1, hRED1  
Peptide ID: 
P10379  
ELISA titre using peptide based assay: 
1:1562500  
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Antigen Specificity: 
Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human ADARB1 with an internal ID of P10379 
Reconstitution and Storage: 
Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 µl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. 
Key Reference: 
Kawahara,Y., Gene 363, 193-201 (2005) 
Quality Control: 
Rabbit IgG purified by protein A chromatography. 
Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. For research use only not for diagnostic, human, or veterinary use.
Western Blot
Suggested dilution at 1.25µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.
Immunoblot

ARP40342-QC9698-WB.jpg
 
Protein_Accession# Protein Size Nucleotide Accession# Swissprot Id Molecular Weight
NP_001103 701 NM_001112 Q4AE79 77kDa
NP_001028221 729 NM_001033049 80kDa
NP_056648 741 NM_015833 81kDa
NP_056649 714 NM_015834 P78563 78kDa