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Cell Adhesion
| FXYD5 (FXYD domain containing ion transport regulator 5) Antibody |
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Description:
FXYD5 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein.
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Species Reactivity:
Human
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Gene Symbol:
FXYD5
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Alias_Symbols:
HSPC113, IWU-1, IWU1, KCT1, OIT2, PRO6241, RIC, dysad
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Peptide ID:
P09024
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ELISA titre using peptide based assay:
1:312500
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Click Here to view more information (protein size, molecular weight, etc)
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Antigen Specificity:
Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human FXYD5 with an internal ID of P09024
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Reconstitution and Storage:
Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 µl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Key Reference:
Batistatou,A., et al., (2005) Br. J. Cancer 93 (12), 1382-1387
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Quality Control:
Rabbit IgG purified by protein A chromatography.
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| Suggested starting concentrations are provided.
Optimal dilutions should be determined by end-user. Differences in calculated versus apparent
molecular weight may be due to post-translational modifications or protein hydrophobicity. For
research use only not for diagnostic, human, or veterinary use. |
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Western Blot
Suggested dilution at 0.625µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.
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Immunoblot
ARP37690-QC6140-WB.jpg
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