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Home > Products >  Antibodies
Home > Products >Antibodies :   Lymphocyte Signaling
Home > Products >Antibodies :   Signaling Intermediates
Home > Products >Antibodies :   Tumor Suppressor Genes & Apoptosis

CFLAR (CASP8 and FADD-like apoptosis regulator) Antibody

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Catalog#   Accession # Size Price Qty
AVARP00022_T100   NP_003870 100µg $198.00
  Description: 
CFLAR might contribute to the carcinogenesis and aggressiveness of endometrial carcinoma and might be a useful prognostic factor in the tumor. CFLAR is specially overexpressed in colon cancers and it might contribute to carcinogenesis of normal colonic mucosa.
Species Reactivity: 
Human  
Gene Symbol: 
CFLAR  
Alias_Symbols: 
HGNC:1876, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLIP, I-FLICE, MRIT, USURPIN  
Peptide ID: 
P01131  
ELISA titre using peptide based assay: 
1:312500  
Click Here to view more information (protein size, molecular weight, etc)
Antigen Specificity: 
Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human CFLAR with an internal ID of P01131 
Reconstitution and Storage: 
Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 µl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. 
Key Reference: 
Kondo,G., et al., (2005) Oncol Rep. 14(5), 1215-22 
Quality Control: 
Rabbit IgG purified by protein A chromatography. 
Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. For research use only not for diagnostic, human, or veterinary use.
Western Blot
Suggested dilution at 1.25µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.
Immunoblot

AVARP00022-QC0240-WB.jpg
 
Protein_Accession# Protein Size Nucleotide Accession# Swissprot Id Molecular Weight
NP_003870 480 NM_003879 O15519 55kDa