APOBEC3G (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G) Antibody

• Catalog#: ARP33540_P050
• Accession#: NP_068594
• Size: 50µg

Description: 
APOBEC3G is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. The protein encoded by this gene has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity.

Species Reactivity:  Human   Gene Symbol:  APOBEC3G   Alias_Symbols:  HGNC:17357, ARP9, CEM15, FLJ12740, MDS019, OTTHUMP00000028911, bK150C2.7, dJ494G10.1   Peptide ID:  P04591   ELISA titre using peptide based assay:  1:1562500   Click Here to view more information (protein size, molecular weight, etc)

Antigen Specificity:  Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human APOBEC3G with an internal ID of P04591  Reconstitution and Storage:  Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 µl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.  Key Reference:  Rose,K.M., et al., (2004) Biol. Chem. 279 (40), 41744-41749  Quality Control:  Rabbit Ig G is purified by peptide affinity chromatography method.  Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. For research use only not for diagnostic, human, or veterinary use.

Western Blot Suggested dilution at 2.0µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. Immunoblot ARP33540-QC2479-WB.jpg Immunohistochemistry 1 ARP33540-QC2479-IHC.jpg

 

Protein_Accession#	Protein Size	Nucleotide Accession#	Swissprot Id	Molecular Weight
NP_068594	384	NM_021822	Q9HC16-2	46kDa