CHRNA1 (cholinergic receptor, nicotinic, alpha 1 (muscle)) Antibody

• Catalog#: ARP34910_P050
• Accession#: NP_000070
• Size: 50µg

Description: 
The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.2 The CHRNA1 gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating.

Species Reactivity:  Human,Rat   Gene Symbol:  CHRNA1   Alias_Symbols:  HGNC:1955, ACHRA, ACHRD, CHRNA, CMS2A, FCCMS, SCCMS   Peptide ID:  P06134   ELISA titre using peptide based assay:  1:2500   Click Here to view more information (protein size, molecular weight, etc)

Antigen Specificity:  Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human CHRNA1 with an internal ID of P06134  Reconstitution and Storage:  Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 µl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.  Key Reference:  Webster,R., et al., (2004) Neurology 62 (7), 1090-1096  Quality Control:  Rabbit Ig G is purified by peptide affinity chromatography method.  Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. For research use only not for diagnostic, human, or veterinary use.

Western Blot Suggested dilution at 0.5µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. Immunoblot ARP34910-QC4465-WB.jpg

 

Protein_Accession#	Protein Size	Nucleotide Accession#	Swissprot Id	Molecular Weight
NP_000070	457	NM_000079	Q53SH4	52kDa