MMP19 (matrix metallopeptidase 19) Antibody

• Catalog#: ARP32314_P050
• Accession#: NP_002420
• Size: 50µg

Description: 
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling. They are also involved in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The function of MMP-19 has not been determined. This gene corresponding to this protein was previously referred to as MMP18 but has been renamed matrix metalloproteinase 19 (MMP19). Multiple transcript variants encoding distict isoforms have been identified for this gene.

Species Reactivity:  Human,Dog   Gene Symbol:  MMP19   Alias_Symbols:  HGNC:7165, MMP18, RASI-1   Peptide ID:  P03301   ELISA titre using peptide based assay:  1:62500   Click Here to view more information (protein size, molecular weight, etc)

Antigen Specificity:  Polyclonal antibody produced in rabbits immunized with a synthetic peptide from human MMP19 with an internal ID of of P03301.  Reconstitution and Storage:  Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 µl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.  Key Reference:  Sadowski,T.,et al., (2003) Mol.Biol.Cell14(11),4569-4580  Quality Control:  Rabbit IgG is purified by peptide affinity chromatography method.  Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. For research use only not for diagnostic, human, or veterinary use.

Western Blot Suggested dilution at 0.5µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. Immunoblot ARP32314-QC1764-WB.jpg Immunohistochemistry 1 ARP32314-QC1764-IHC-1.jpg Immunohistochemistry 2 ARP32314-QC1764-IHC-2.jpg

 

Protein_Accession#	Protein Size	Nucleotide Accession#	Swissprot Id	Molecular Weight
NP_002420	508	NM_002429	Q99542	56 kDa