HOXD3 (homeobox D3) Antibody

• Catalog#: ARP31964_P050
• Accession#: NP_008829
• Size: 50µg

Description: 
HOXD3 (homeobox D3) belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that remove the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. HOXD3 may play a role in the regulation of cell adhesion processes.

Species Reactivity:  Human,Dog   Gene Symbol:  HOXD3   Alias_Symbols:  HGNC:5137, HOX1D, HOX4, HOX4A, Hox-4.1, MGC10470   Peptide ID:  P02861   ELISA titre using peptide based assay:  1:62500   Click Here to view more information (protein size, molecular weight, etc)

Antigen Specificity:  Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of human HOXD3 with an internal ID of P02861.  Reconstitution and Storage:  Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.  Key Reference:  Boudreau,N.J., et al., (2004) J.Biol.Chem.279(6),4862-4868  Quality Control:  Rabbit Ig G is purified by peptide affinity chromatography method.  Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. For research use only not for diagnostic, human, or veterinary use.

Western Blot Suggested dilution at 1.0-2.0µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,039 as second antibody. Immunoblot ARP31964-QC1727-WB.jpg Immunohistochemistry 1 ARP31964-QC1727-IHC-1.jpg Immunohistochemistry 2 ARP31964-QC1727-IHC-2.jpg

 

Protein_Accession#	Protein Size	Nucleotide Accession#	Swissprot Id	Molecular Weight
NP_008829	432	NM_006898	P31249	46 kDa