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Home > Products >  Antibodies
Home > Products >  Transcription Factor Antibodies
Home > Products >Transcription Factor Antibodies :   Nuclear Receptor
Home > Products >Transcription Factor Antibodies :   Zinc-Coordinating

NR4A1 (nuclear receptor subfamily 4, group A, member 1) Antibody

Preview
Catalog#   Accession # Size Price Qty
ARP31941_P050   NP_775181 50µg $260.00
  Description: 
NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis.
Species Reactivity: 
Human,Dog  
Gene Symbol: 
NR4A1  
Alias_Symbols: 
HGNC:7980, GFRP1, HMR, MGC9485, N10, NAK-1, NGFIB, NP10, NUR77, TR3  
Peptide ID: 
P02838  
ELISA titre using peptide based assay: 
1:312500  
Click Here to view more information (protein size, molecular weight, etc)
Antigen Specificity: 
Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human NR4A1 with an internal ID of P02838 
Reconstitution and Storage: 
Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 µl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. 
Key Reference: 
Yoo,Y.G., , et al., (2004) J. Biol. Chem. 279 (51), 53365-53373 
Quality Control: 
Rabbit Ig G is purified by peptide affinity chromatography method. 
Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. For research use only not for diagnostic, human, or veterinary use.
Western Blot
Suggested dilution at 2.0/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.
Immunoblot

ARP31941-QC1452WB.jpg
Immunohistochemistry 1

ARP31941-QC1452IHC-1.jpg
Immunohistochemistry 2

ARP31941-QC1452IHC-2.jpg
 
Protein_Accession# Protein Size Nucleotide Accession# Swissprot Id Molecular Weight
NP_775181 325 NM_173158 P22736 34 kDa