Catalog No: OAAN01866
Price: $0.00
SKU
OAAN01866
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for anti-CCM2 (OAAN01866)
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationWB, IHC
Reconstitution and StorageStore at -20C. Avoid repeated freeze/thaw cycles.
ImmunogenRecombinant protein of human CCM2
PurificationAffinity purified against immunogen
Preservative0.02% Sodium Azide
Application InfoWB: 1:500 - 1:2,000. IHC: 1:50 - 1:200
Storage BufferPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene SymbolCCM2
Gene Full NameCCM2 scaffolding protein
Alias SymbolsOSM, C7orf22, PP10187
NCBI Gene Id83605
Protein NameCerebral cavernous malformations 2 protein
Description of TargetThis gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.
Uniprot IDQ9BSQ5
Protein Accession #NP_001025006.1
Nucleotide Accession #NM_001029835.2
Molecular Weight49 kDa
  1. What is the species homology for "CCM2 Antibody (OAAN01866)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "CCM2 Antibody (OAAN01866)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "CCM2 Antibody (OAAN01866)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CCM2 Antibody (OAAN01866)"?

    This target may also be called "OSM, C7orf22, PP10187" in publications.

  5. What is the shipping cost for "CCM2 Antibody (OAAN01866)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CCM2 Antibody (OAAN01866)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CCM2 Antibody (OAAN01866)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "49 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CCM2 Antibody (OAAN01866)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CCM2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CCM2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CCM2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CCM2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CCM2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CCM2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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