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- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
Datasheets/Manuals | Printable datasheet for anti-CAV1 antibody - OAPA00353 |
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Predicted Species Reactivity | Human |
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Product Format | Liquid PBS, pH-7.4, & 0.1% Sodium Azide Physical Appearance: Sterile Filtered clear solution |
Clonality | Monoclonal |
Clone | PAT4C1AT |
Isotype | Mouse IgG2b heavy chain and kappa light chain. |
Host | Mouse |
Application | WB |
Reconstitution and Storage | For periods up to 1 month store at 4C, for periods up to 12 months, store at -20C. Prevent freeze thaw cycles. Please prevent freeze/thaw cycles. |
Immunogen | The immunogen for anti-CAV1 antibody: anti-human CAV1 mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CAV1 amino acids 1-104 purified from E. coli. |
Purification | CAV1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Concentration | 1 mg/ml |
Purity | CAV1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Application Info | WB: 1:250~1000 (Recommended starting dilution is 1:500) |
Application Data | CAV1 antibody has been tested by ELISA, Western blot to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. |
Gene Symbol | CAV1 |
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Alias Symbols | CGL3, PPH3, BSCL3, LCCNS, VIP21, MSTP085 |
NCBI Gene Id | 857 |
Protein Name | Caveolin-1 |
Description of Target | The scaffolding protein encoded by the CAV1 gene is the key component of the caveolae plasma membranes found in most cell types. Cholesterol is vital for caveolae formation and maintenance, and caveolae structure is highly sensitive to cholesterol depletion or treatment with cholesterol binding drugs. CAV1 can tightly and specifically bind free cholesterol and artificial cholesterol containing vesicles. Caveolin 1 links integrin subunits to the tyrosine kinase FYN, which is an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. CAV1 is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase. Caveolin 1 and caveolin 2 are positioned next to each other on chromosome 7 and express co-localizing proteins which form a stable hetero-oligomeric complex cascade. Mutations in the CAV1 gene are linked to Berardinelli-Seip congenital lipodystrophy. |
Uniprot ID | Q03135 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "CAV1 Antibody (OAPA00353)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "CAV1 Antibody (OAPA00353)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "CAV1 Antibody (OAPA00353)" provided in?
This item is provided in "Liquid PBS, pH-7.4, & 0.1% Sodium Azide
Physical Appearance: Sterile Filtered clear solution".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "CAV1 Antibody (OAPA00353)"?
This target may also be called "CGL3, PPH3, BSCL3, LCCNS, VIP21, MSTP085" in publications.
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What is the shipping cost for "CAV1 Antibody (OAPA00353)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "CAV1 Antibody (OAPA00353)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "CAV1 Antibody (OAPA00353)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "CAV1 Antibody (OAPA00353)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CAV1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CAV1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CAV1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CAV1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CAV1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CAV1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.