Catalog No: AVARP09019_T100
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AVARP09019_T100
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Datasheets/ManualsPrintable datasheet for anti-CAV1 (AVARP09019_T100) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human CAV1
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%
Peptide SequenceSynthetic peptide located within the following region: MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEID
Concentration1.0 mg/ml
Blocking PeptideFor anti-CAV1 (AVARP09019_T100) antibody is Catalog # AAP30144 (Previous Catalog # AAPS08602)
ReferenceWehner,K.A. Am. J. Physiol., Cell Physiol. 290 (5), C1273-C1274 (2006)
Description
Gene SymbolCAV1
Gene Full NameCaveolin 1, caveolae protein, 22kDa
Alias SymbolsCGL3, PPH3, BSCL3, LCCNS, VIP21, MSTP085
NCBI Gene Id857
Protein NameCaveolin-1
Description of TargetThe scaffolding protein is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression.The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.
Uniprot IDQ03135
Protein Accession #NP_001744
Nucleotide Accession #NM_001753
Protein Size (# AA)178
Molecular Weight20kDa
Protein InteractionsTFRC; ABCC1; UBC; RPA3; ATG5; ATG12; RPA2; RPA1; PTGIS; EGFR; VCP; UFD1L; PTGS2; PTGS1; ESR1; DERL1; VIMP; ATP4A; CAV2; GLIPR2; KDR; PROCR; F2R; BID; NOS3; HSP90AA1; FAS; ACTB; MALL; NF1; LRP6; KCNMA1; BMPR2; BMPR1A; AXIN1; PPP2CA; MCL1; ITPR3; ID1; TENC1
  1. What is the species homology for "CAV1 Antibody - N-terminal region (AVARP09019_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep".

  2. How long will it take to receive "CAV1 Antibody - N-terminal region (AVARP09019_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "CAV1 Antibody - N-terminal region (AVARP09019_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CAV1 Antibody - N-terminal region (AVARP09019_T100)"?

    This target may also be called "CGL3, PPH3, BSCL3, LCCNS, VIP21, MSTP085" in publications.

  5. What is the shipping cost for "CAV1 Antibody - N-terminal region (AVARP09019_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CAV1 Antibody - N-terminal region (AVARP09019_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CAV1 Antibody - N-terminal region (AVARP09019_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "20kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CAV1 Antibody - N-terminal region (AVARP09019_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CAV1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CAV1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CAV1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CAV1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CAV1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CAV1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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