BMPR1A Antibody - N-terminal region (ARP73773_P050)

Catalog No: ARP73773_P050

Host: Rabbit
Target Name: BMPR1A
Sample Type: Jurkat Whole Cell lysates
Antibody Dilution: 1.0ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human BMPR1A
• Purification: Affinity Purified
• Peptide Sequence: Synthetic peptide located within the following region: GMKSDSDQKKSENGVTLAPEDTLPFLKCYCSGHCPDDAINNTCITNGHCF
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-BMPR1A (ARP73773_P050) antibody is Catalog # AAP73773

Target Info

• Gene Symbol: BMPR1A
• Alias Symbols: ALK3, SKR5, CD292, ACVRLK3, 10q23del
• NCBI Gene Id: 657
• Description of Target: The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
• Uniprot ID: P36894
• Protein Accession #: XP_005270121
• Protein Size (# AA): 532
• Molecular Weight: 58kDa
• Protein Interactions: UBC; USP15; BMPR1A; ACVR1; PEG10; CAV1; HSP90AA1; BAMBI; SMAD7; SMAD6; SMAD1; MYC; SMURF1; Nedd4; NEDD4L; FST; IGSF1; TSC22D1; RUNX2; SF3B4; GDF6; ZMYND11; TGFBRAP1; BMPR1B; TAB1; GDF9; GDF5; BMPR2; HOXC8; BMP7; BMP6; BMP5; BMP4; BMP2; FKBP1A; FKBP1B;