ATP11C Antibody - middle region (OAAB02861)

Catalog No: OAAB02861

Size:400ul

ATP11C Antibody (Center) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the ATP11C antibody detected ATP11C protein (arrow).

ATP11C Antibody (Center) western blot analysis in CHO cell lysates (35ug/lane).This demonstrates the ATP11C antibody detected the ATP11C protein (arrow).

ATP11C Antibody (Center immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ATP11C Antibody (Center for immunohistochemistry. Clinical relevance has not been evaluated.

ATP11C Antibody (Center) flow cytometric analysis of 293 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Info

• Predicted Species Reactivity: Human, Mouse, Hamster
• Product Format: Liquid. PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: WB, FC, IHC-P
  Function: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. Required for B cell differentiation past the pro-B cell stage. Seems to mediate phosphatidylserine (PS) flipping in pro-B cells. May be involved in the transport of cholestatic bile acids (By similarity).
  Cellular Location: Cell membrane; Multi-pass membrane protein Endoplasmic reticulum membrane Note=Efficient exit from the endoplasmic reticulum requires the presence of TMEM30A. Some cell membrane localization observed in the presence of TMEM30B.
  Tissue Location Widely expressed.
  
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This ATP11C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 589-616 amino acids from the Central region of human ATP11C.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse, Hamster
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Intended Use:
  For research use only and not for use in diagnostic or therapeutic procedures.
• Application Info: WB: 1:1000
  IHC-P: 1:50~100
  FC: 1:10~50
• Other Applications Image 1 Data: ATP11C Antibody (Center) flow cytometric analysis of 293 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Target Info

• Gene Symbol: ATP11C
• Alias Symbols: ATPIG, ATPIQ, HACXL
• NCBI Gene Id: 286410
• Protein Name: Probable phospholipid-transporting ATPase IG
• Uniprot ID: Q8NB49
• Protein Accession #: NP_001010986.1
• Molecular Weight: 129477 Da