ATN1 Antibody - N-terminal region (ARP34153_P050)

Catalog No: ARP34153_P050

Click here to learn more about Aviva's By-Request Conjugation Service.

25 ug of the indicated Human whole cell extracts was loaded onto a 6-18% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment.

WB Suggested Anti-ATN1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Human Placenta

WB Suggested Anti-ATN1 Antibody
Positive Control: Lane1: 30ug human fibroblasts
Primary Antibody Dilution : 1:500
Secondary Antibody : Anti-rabbit-HRP
Secondry Antibody Dilution : 1:1000
Submitted by: Anonymous

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ATN1
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 93%; Dog: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 100%; Rat: 93%
• Peptide Sequence: Synthetic peptide located within the following region: VSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAP
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-ATN1 (ARP34153_P050) antibody is Catalog # AAP34153 (Previous Catalog # AAPP23746)
• Sample Type Confirmation:

  There is BioGPS gene expression data showing that ATN1 is expressed in 721_B

• Reference: Alluri,R.V., (2007) Mol. Cells 24 (3), 338-342

Target Info

• Gene Symbol: ATN1
• Gene Full Name: Atrophin 1
• Alias Symbols: B37, HRS, NOD, DRPLA, CHEDDA, D12S755E
• NCBI Gene Id: 1822
• Protein Name: Atrophin-1
• Description of Target: Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within ATN1. The protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.
• Uniprot ID: P54259
• Protein Accession #: NP_001931
• Nucleotide Accession #: NM_001940
• Protein Size (# AA): 1190
• Molecular Weight: 125kDa
• Protein Interactions: WWOX; Dlg4; SIAH1; HINFP; LRP2; RBFOX1; EFEMP2; NOC2L; RCHY1; ZMYND8; RBFOX2; KAT6B; SSPO; RAD54L2; ZSWIM8; WDR5; WWP2; WWP1; RBPMS; SPAG5; FBLN5; BAIAP2; PSME3; CBFA2T2; CHRD; NCK2; LTBP4; RBM10; KAT6A; BAG6; PRRC2A; TRIP6; TEP1; SLIT1; SIAH2; PSMA3; PLS