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Catalog No: OAAB10124
Size:400ul
Price: $438.00
SKU
OAAB10124
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for OAAB10124
Product Info
Predicted Species ReactivityHuman
Product FormatPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
ClonalityPolyclonal
IsotypeIg
HostRabbit
ApplicationWB
Additional InformationPrecautions: ARHGAP24 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
::Function: Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis
::Cellular Location: Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell junction, focal adhesion. Cell projection Note=Localizes to actin stress fibers. In migrating cells, localizes to membrane lamellae and protusions
Tissue Location: Isoform 1 is widely expressed with a higher level in kidney. Isoform 2 is mainly expressed in endothelial cells
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis ARHGAP24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 587-616 amino acids from the C-terminal region of human ARHGAP24.
Predicted Homology Based on Immunogen SequenceHuman
ConcentrationApproximately 0.5mg/ml. Actual concentration varies with each lot.
Application InfoWB: 1:1000
Gene SymbolARHGAP24
Alias Symbolsp73, FILGAP, RCGAP72, RC-GAP72, p73RhoGAP
NCBI Gene Id83478
Protein NameRho GTPase-activating protein 24
Description of TargetPeptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Uniprot IDQ8N264
Protein Accession #NP_001020787.2
Molecular Weight84258 Da
  1. What is the species homology for "ARHGAP24 Antibody - C-terminal region (OAAB10124)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "ARHGAP24 Antibody - C-terminal region (OAAB10124)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "ARHGAP24 Antibody - C-terminal region (OAAB10124)" provided in?

    This item is provided in "Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ARHGAP24 Antibody - C-terminal region (OAAB10124)"?

    This target may also be called "p73, FILGAP, RCGAP72, RC-GAP72, p73RhoGAP" in publications.

  5. What is the shipping cost for "ARHGAP24 Antibody - C-terminal region (OAAB10124)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ARHGAP24 Antibody - C-terminal region (OAAB10124)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ARHGAP24 Antibody - C-terminal region (OAAB10124)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "84258 Da".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ARHGAP24 Antibody - C-terminal region (OAAB10124)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ARHGAP24"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ARHGAP24"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ARHGAP24"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ARHGAP24"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ARHGAP24"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ARHGAP24"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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