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ARC antibody - middle region (ARP36563_P050)

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100 ul
$289.00
In Stock

Conjugation Options

ARP36563_P050-FITC Conjugated

ARP36563_P050-HRP Conjugated

ARP36563_P050-Biotin Conjugated

Free trial-size samples may be available for this item. Please go here for more information.
Gene Symbol:
ARC
NCBI Gene Id:
23237
Official Gene Full Name:
Activity-regulated cytoskeleton-associated protein
Protein Name:
Activity-regulated cytoskeleton-associated protein
Swissprot Id:
Q7LC44
Protein Accession #:
NP_056008
Nucleotide Accession #:
NM_015193
Alias Symbols:
KIAA0278, Arg3.1
Replacement Item:
This antibody may replace item sc-136278 from Santa Cruz Biotechnology.
Description of Target:
ARC is required for consolidation of synaptic plasticity as well as formation of long-term memory. It regulates endocytosis of AMPA receptors in response to synaptic activity. The protein is also required for homeostatic synaptic scaling of AMPA receptors.
Protein Size (# AA):
396
Molecular Weight:
45kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ARC.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ARC.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human ARC
Species Reactivity:
Cow, Goat, Guinea Pig, Human, Mouse, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Goat: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%
Complete computational species homology data:
Anti-ARC (ARP36563_P050)
Peptide Sequence:
Synthetic peptide located within the following region: ELDLPQKQGEPLDQFLWRKRDLYQTLYVDADEEEIIQYVVGTLQPKLKRF
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBE3A; UBC; KRT15;
Blocking Peptide:
For anti-ARC (ARP36563_P050) antibody is Catalog # AAP36563 (Previous Catalog # AAPP07714)
Datasheets / Downloads:
Printable datasheet for anti-ARC (ARP36563_P050) antibody
Target Reference:
Foo,R.S., (2007) Proc. Natl. Acad. Sci. U.S.A. 104 (52), 20826-20831

Product Protocols: ARC antibody tested with Human Transfected 293T Cells (ARP36563_P050)

Aviva Systems Biology is the original manufacturer of this ARC antibody (ARP36563_P050)

Click here to view the ARC antibody Western Blot Protocol

Product Datasheet Link: ARC antibody (ARP36563_P050)

WB Suggested Anti-ARC Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Transfected 293T

Western Blot image:


Description of Target: ARC is required for consolidation of synaptic plasticity as well as formation of long-term memory. It regulates endocytosis of AMPA receptors in response to synaptic activity. The protein is also required for homeostatic synaptic scaling of AMPA receptors.

Questions pertaining to this data can be directed to techsupport@avivasysbio.com

Aviva Systems Biology’s ARC antibody (ARP36563_P050) has been tested using other cell lysates and tissues. To obtain more data about this antibody please email us at info@avivasysbio.com.

To order by phone call us at (888) 880-0001, fax us at (858) 552-6975 or send an email to info@avivasysbio.com. Aviva manufactures this antibody so we can offer the best price. Please contact us to request pricing information.

All of Aviva’s products are guaranteed for the applications and experimental sample types mentioned in the datasheet below. Are you curious if this product will work for you? Please contact us at techsupport@avivasysbio.com

 
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