ARAP1 Antibody (OAGA00480)

Catalog No: OAGA00480

Size:100 ul

Sample (30 ug of whole cell lysate)
A: H1299
5% SDS PAGE
OAGA00480 diluted at 1:1000

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB
• Additional Information: Background: The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  Positive Controls: A431, H1299, HeLa, HepG2
  Cellular Localization: Cytoplasm, Golgi apparatus, Golgi stack membrane, Cell membrane
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Synthetic peptide corresponding to a region within amino acids 1388 and 1450 of ARAP1 (Uniprot ID#Q96P48)
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 1 mg/ml
• Application Info: Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: ARAP1
• Gene Full Name: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
• Alias Symbols: CENTD2
• NCBI Gene Id: 116985
• Protein Name: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
• Uniprot ID: Q96P48
• Protein Accession #: NP_001035207.1
• Molecular Weight: 162 kDa