Catalog No: OAPA00211 (Formerly GWB-BSP881)
Size:5UG
Price: $75.00
SKU
OAPA00211
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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APP Antibody (OAPA00211)

Datasheets/ManualsPrintable datasheet for anti-APP antibody - OAPA00211
Product Info
Predicted Species ReactivityHuman
Product Format1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
ClonalityMonoclonal
ClonePJ4H9AT.
IsotypeMouse IgG2b heavy chain and kappa light chain.
HostMouse
ApplicationWB
::Product Type: Mouse Anti Human Monoclonal.
::Product Introduction: APP is a cell surface receptor and transmembrane precursor protein which is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in the APP gene are implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).
Reconstitution and StorageFor periods up to 1 month store at 4C, for longer periods of time, store at -20C. Prevent freeze thaw cycles.
Stability: 12 months at -20C. 1 month at 4C.
ImmunogenThe immunogen for anti-APP antibody: anti-human APP mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human APP amino acids 18-289 purified from E. coli.
PurityAPP antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Application InfoAPP antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 2,000. Recommended starting dilution is 1:1,000.
Gene SymbolApp
Alias SymbolsA, C, Ag, Abe, bet, Abpp, Adap, Cvap, Abeta, betaApp, E030013M08Rik
NCBI Gene Id11820
Protein NameAmyloid beta A4 protein
Description of TargetMouse Anti Human Amyloid Beta A4 Protein
Uniprot IDP12023
  1. What is the species homology for "APP Antibody (OAPA00211)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "APP Antibody (OAPA00211)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "APP Antibody (OAPA00211)" provided in?

    This item is provided in "1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "APP Antibody (OAPA00211)"?

    This target may also be called "A, C, Ag, Abe, bet, Abpp, Adap, Cvap, Abeta, betaApp, E030013M08Rik" in publications.

  5. What is the shipping cost for "APP Antibody (OAPA00211)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "APP Antibody (OAPA00211)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "APP Antibody (OAPA00211)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "APP Antibody (OAPA00211)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "APP"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "APP"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "APP"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "APP"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "APP"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "APP"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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