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| Datasheets/Manuals | Printable datasheet for OAAB14718 |
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| Predicted Species Reactivity | Mouse |
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| Product Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Clonality | Polyclonal |
| Isotype | Ig |
| Host | Rabbit |
| Application | WB |
| Additional Information | Precautions: APH1A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| :: | Function: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex |
| :: | Cellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, Golgi stack membrane; Multi- pass membrane protein. Note=Predominantly located in the endoplasmic reticulum and in the cis-Golgi Tissue Location: Widely expressed. Expressed in leukocytes, lung, placenta, small intestine, liver, kidney, spleen thymus, skeletal muscle, heart and brain. Isoform 1 and isoform 2 are nearly expressed at the same level |
| Reconstitution and Storage | Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | This APH1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human APH1A. |
| Predicted Homology Based on Immunogen Sequence | Mouse |
| Concentration | Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Application Info | WB: 1:1000 |
| Gene Symbol | APH1A |
|---|---|
| Alias Symbols | APH-1, APH-1A, CGI-78, 6530402N02Rik |
| NCBI Gene Id | 51107 |
| Protein Name | Gamma-secretase subunit APH-1A |
| Description of Target | Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |
| Uniprot ID | Q96BI3 |
| Protein Accession # | NP_001071096.1 |
| Molecular Weight | 28996 Da |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "APH1A Antibody - N-terminal region (OAAB14718)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Mouse".
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How long will it take to receive "APH1A Antibody - N-terminal region (OAAB14718)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "APH1A Antibody - N-terminal region (OAAB14718)" provided in?
This item is provided in "Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "APH1A Antibody - N-terminal region (OAAB14718)"?
This target may also be called "APH-1, APH-1A, CGI-78, 6530402N02Rik" in publications.
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What is the shipping cost for "APH1A Antibody - N-terminal region (OAAB14718)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "APH1A Antibody - N-terminal region (OAAB14718)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "APH1A Antibody - N-terminal region (OAAB14718)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "28996 Da".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "APH1A Antibody - N-terminal region (OAAB14718)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "APH1A"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "APH1A"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "APH1A"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "APH1A"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "APH1A"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "APH1A"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
