Catalog No: OAPB01089
Size:100UG
Price: $461.00
SKU
OAPB01089
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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Datasheets/ManualsPrintable datasheet for APC2 Antibody (OAPB01089) (OAPB01089)
Product Info
Predicted Species ReactivityHuman|Mouse
Product FormatLiquid. APC2 Antibody is supplied in PBS containing 0.02% sodium azide.
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
ApplicationEnzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot
::Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and StorageAPC2 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ImmunogenAPC2 antibody was raised against an 18 amino acid synthetic peptide near the center of human APC2. The immunogen is located within amino acids 240 - 290 of APC2.
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceHuman; Mouse
Concentration1 mg/ml
Blocking PeptideFor anti-APC2 antibody is Catalog # OEPB03207
Application InfoAPC2 antibody can be used for detection of APC2 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
ReferenceJM Peters. The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat. Rev. Mol. Cell Biol.2006; 7:644-56.;Jorgensen PM, Graslund S, Betz R, et al. Characterisation of the human APC1, the largest subunit of the anaphase-promoting complex. Gene2001; 262:51-9.;Yu H, Peters JM, King RW, et al. Identification of a cullin homology region in a subunit of the anaphase-promoting complex. Science1998; 279:1219-22.;Zacharie W, Shevchenko A, Andrews PD, et al. Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins. Science1998; 1216-19.
Gene SymbolAPC2
Gene Full NameAPC regulator of WNT signaling pathway 2
Alias Symbolsadenomatosis polyposis coli 2;adenomatous polyposis coli like;adenomatous polyposis coli protein 2;Adenomatous polyposis coli protein-like;APC2, WNT signaling pathway regulator;APCL.
NCBI Gene Id10297
Protein NameAdenomatous polyposis coli protein 2|APCL protein [Homo sapiens]
Description of TargetStabilizes microtubules and may regulate actin fiber dynamics through the activation of Rho family GTPases (PubMed:25753423). May also function in Wnt signaling by promoting the rapid degradation of CTNNB1 (PubMed:10021369, PubMed:11691822, PubMed:9823329).
Uniprot IDO95996
Protein Accession #https://www.ncbi.nlm.nih.gov/protein/BAA34611
  1. What is the species homology for "APC2 Antibody (OAPB01089)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".

  2. How long will it take to receive "APC2 Antibody (OAPB01089)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "APC2 Antibody (OAPB01089)" provided in?

    This item is provided in "Liquid. APC2 Antibody is supplied in PBS containing 0.02% sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "APC2 Antibody (OAPB01089)"?

    This target may also be called "adenomatosis polyposis coli 2;adenomatous polyposis coli like;adenomatous polyposis coli protein 2;Adenomatous polyposis coli protein-like;APC2, WNT signaling pathway regulator;APCL." in publications.

  5. What is the shipping cost for "APC2 Antibody (OAPB01089)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "APC2 Antibody (OAPB01089)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "APC2 Antibody (OAPB01089)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "APC2 Antibody (OAPB01089)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "APC2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "APC2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "APC2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "APC2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "APC2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "APC2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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