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Datasheets/Manuals | Printable datasheet for APC2 Antibody (OAPB01089) (OAPB01089) |
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Predicted Species Reactivity | Human|Mouse |
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Product Format | Liquid. APC2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Clonality | Polyclonal |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot |
:: | Buffer: Antibody is supplied in PBS containing 0.02% sodium azide. |
Reconstitution and Storage | APC2 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Immunogen | APC2 antibody was raised against an 18 amino acid synthetic peptide near the center of human APC2. The immunogen is located within amino acids 240 - 290 of APC2. |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Human; Mouse |
Concentration | 1 mg/ml |
Blocking Peptide | For anti-APC2 antibody is Catalog # OEPB03207 |
Application Info | APC2 antibody can be used for detection of APC2 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user) |
Reference | JM Peters. The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat. Rev. Mol. Cell Biol.2006; 7:644-56.;Jorgensen PM, Graslund S, Betz R, et al. Characterisation of the human APC1, the largest subunit of the anaphase-promoting complex. Gene2001; 262:51-9.;Yu H, Peters JM, King RW, et al. Identification of a cullin homology region in a subunit of the anaphase-promoting complex. Science1998; 279:1219-22.;Zacharie W, Shevchenko A, Andrews PD, et al. Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins. Science1998; 1216-19. |
Gene Symbol | APC2 |
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Gene Full Name | APC regulator of WNT signaling pathway 2 |
Alias Symbols | adenomatosis polyposis coli 2;adenomatous polyposis coli like;adenomatous polyposis coli protein 2;Adenomatous polyposis coli protein-like;APC2, WNT signaling pathway regulator;APCL. |
NCBI Gene Id | 10297 |
Protein Name | Adenomatous polyposis coli protein 2|APCL protein [Homo sapiens] |
Description of Target | Stabilizes microtubules and may regulate actin fiber dynamics through the activation of Rho family GTPases (PubMed:25753423). May also function in Wnt signaling by promoting the rapid degradation of CTNNB1 (PubMed:10021369, PubMed:11691822, PubMed:9823329). |
Uniprot ID | O95996 |
Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/BAA34611 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "APC2 Antibody (OAPB01089)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
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How long will it take to receive "APC2 Antibody (OAPB01089)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "APC2 Antibody (OAPB01089)" provided in?
This item is provided in "Liquid. APC2 Antibody is supplied in PBS containing 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "APC2 Antibody (OAPB01089)"?
This target may also be called "adenomatosis polyposis coli 2;adenomatous polyposis coli like;adenomatous polyposis coli protein 2;Adenomatous polyposis coli protein-like;APC2, WNT signaling pathway regulator;APCL." in publications.
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What is the shipping cost for "APC2 Antibody (OAPB01089)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "APC2 Antibody (OAPB01089)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "APC2 Antibody (OAPB01089)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "APC2 Antibody (OAPB01089)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "APC2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "APC2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "APC2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "APC2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "APC2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "APC2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.