Catalog No: OAPC00084
Size:100 ul
Price: $335.00
SKU
OAPC00084
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for OAPC00084
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid. Contains 10 mM sodium azide.
ClonalityPolyclonal
HostChicken
ApplicationWB, IF
Additional InformationPackaging :
Liquid. Contains 10 mM sodium azide.
Reconstitution and StorageStore at -20C in undiluted aliquots; stable for at least 1 year. Avoid freeze/thaw cycles.
ImmunogenRecombinant human Vimentin purified from E. coli.
PurificationTotal IgY fraction.
Predicted Homology Based on Immunogen SequenceHuman; Mouse; Rat
SpecificitySpecific for the ~50kDa Vimentin protein.
Application InfoThe antibody has been directly tested for reactivity in human, mouse and rat. It is expected that it will work on other mammalian tissues.
Western blot of NIH 3T3 cells showing specific immunolabeling of the ~50k Vimentin protein.
Mixed neuron/glial cultures stained with anti-Vimentin (green) and rabbit anti-GFAP antibody (catalog #OAPC00114) (red). Vimentin is expressed alone in fibroblastic and endothelial cells, which are the flattened cells in the middle of the image which appear green. Astrocytes may express primarily GFAP, or GFAP and vimentin, and so appear red (GFAP only) or golden yellow (GFAP and Vimentin). In cells which express both GFAP and vimentin, the two proteins assemble to produce heteropolymer filaments.
ReferenceNieminen M, Henttinen T, Merinen M, Marttila-Ichihara F, Eriksson JE, Jalkanen S (2006)
Vimentin function in lymphocyte adhesion and transcellular migration. Nat Cell Biol
8(2):156-62.
Zhao Y, Yan Q, Long X, Chen X, Wang Y (2008) Vimentin affects the mobility and invasiveness of prostate cancer cells. Cell Biochem Funct. May 8 [Epub ahead of print]
Gene SymbolVIM
NCBI Gene Id7431
Protein NameVimentin
Description of TargetVimentin is the major protein subunit of the 10nm or intermediate filaments (IFs) found in many kinds of mesenchymal and epithelial cells as well as developing neuronal and astrocytic precursor cells in the CNS. Vimentin is thought to be critically involved in lymphocyte adhesion and transmigration (Nieminen M et al. 2006). Copolymers are frequently formed between vimentin and other IFs, such as GFAP (in many kinds of astrocytes), desmin (in muscle cells) and neurofilament proteins (in developing neurons). Antibodies to vimentin are useful in studies of stem cells and generally to reveal the filamentous cytoskeleton. Recent studies suggest that vimentin affects prostate cancer cells motility and invasiveness (Zhao et al. 2008).
Uniprot IDP08670
Protein Accession #NP_003371.2
Molecular Weight~50kDa
  1. What is the species homology for "Anti-Vimentin (OAPC00084)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "Anti-Vimentin (OAPC00084)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "Anti-Vimentin (OAPC00084)" provided in?

    This item is provided in "Liquid. Contains 10 mM sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Anti-Vimentin (OAPC00084)"?

    This target may also be called "" in publications.

  5. What is the shipping cost for "Anti-Vimentin (OAPC00084)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Anti-Vimentin (OAPC00084)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Anti-Vimentin (OAPC00084)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "~50kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Anti-Vimentin (OAPC00084)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "VIM"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "VIM"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "VIM"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "VIM"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "VIM"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "VIM"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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